Assessment of iridoid profiles in the growth period of aerial parts of Pseudolysimachion rotundum var. subintegrum and their antioxidant and MUC5AC inhibitory potential

Assessment of iridoid profiles in the growth period of aerial parts of Pseudolysimachion rotundum var. subintegrum and their antioxidant and MUC5AC inhibitory potential

Abstract YPL-001 is a drug substance of Pseudolysimachion rotundum var. subintegrum and has been reported to be a potent COPD inhibitor. For the first time, this study demonstrated a correlation among the iridoid constituents, antioxidants, and MUC5AC inhibition activities in P. rotundum during diff...

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Main Authors: Soobin Song, Doo-Young Kim, Seon Min Oh, So-Yeun Woo, Il-joo Kim, Mun-Ock Kim, Ji-Yoon Park, Namho Kim, Hae-Young Kim, Juhee Lee, Sang Yoon Kim, Bang Yeon Hwang, Hyung Won Ryu, Sei-Ryang Oh
Format: Article
Language:English
Published: SpringerOpen 2023-07-01
Series:Applied Biological Chemistry
Subjects:
Pseudolysimachion rotundum var. Subintegrum
Growth stages
Quality control
Antioxidant
MUC5AC
Online Access:https://doi.org/10.1186/s13765-023-00796-0
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