Mining versatile feruloyl esterases: phylogenetic classification, structural features, and deep learning model

Mining versatile feruloyl esterases: phylogenetic classification, structural features, and deep learning model

Abstract Feruloyl esterases (FEs, EC 3.1.1.73) play a crucial role in biological synthesis and metabolism. However, the identification of versatile FEs, capable of catalyzing a wide range of substrates, remains a challenge. In this study, we obtained 2085 FE sequences from the BRENDA database and in...

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Bibliographic Details
Main Authors: Liang Guo, Yuxin Dong, Deyong Zhang, Xinrong Pan, Xinjie Jin, Xinyu Yan, Yin Lu
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Bioresources and Bioprocessing
Subjects:
Feruloyl esterases
Enzyme similarity network
Phylogenetic analysis
Molecular dynamics simulations
Deep learning
Online Access:https://doi.org/10.1186/s40643-024-00835-8
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