Regeneration of the Fibula with Unidirectional Porous Hydroxyapatite
A fibula graft is one of the most common orthopedic procedures for reconstruction of a bone defect, and some complications related to persistent defects of the fibula have been reported previously. We believe that regeneration of the fibula may be critical for postoperative function and prevention o...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Orthopedics |
| Online Access: | http://dx.doi.org/10.1155/2019/9024643 |
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| author | Koji Demiya Toshiyuki Kunisada Eiji Nakata Joe Hasei Toshifumi Ozaki |
| author_facet | Koji Demiya Toshiyuki Kunisada Eiji Nakata Joe Hasei Toshifumi Ozaki |
| author_sort | Koji Demiya |
| collection | DOAJ |
| description | A fibula graft is one of the most common orthopedic procedures for reconstruction of a bone defect, and some complications related to persistent defects of the fibula have been reported previously. We believe that regeneration of the fibula may be critical for postoperative function and prevention of complications. This report describes a 9-year-old female with Ewing sarcoma of the pelvis who was treated with the double-barrel fibula grafts for pelvic bone defect following tumor resection. The defect after fibular resection was filled with unidirectional porous hydroxyapatite (UDPHAp) implants. A plain radiograph revealed new bone formation and a callus-like structure at one month after surgery and bony union between each UDPHAp implant 5 months after surgery. Resorption of implanted UDPHAp was identified, and partial remodeling of the bone marrow cavity could be seen 1 year 2 months after surgery. A radiograph at final follow-up (5 years 10 months after surgery) demonstrated almost complete absorption of the implanted UDPHAp and clear formation of the cortex and bone marrow in the resected part of the fibula. The patient is able to walk well without any walking supports and to take part in sports activities. |
| format | Article |
| id | doaj-art-3b840ba8b0114af593a301455d8463a0 |
| institution | Kabale University |
| issn | 2090-6749 2090-6757 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Orthopedics |
| spelling | doaj-art-3b840ba8b0114af593a301455d8463a02025-02-03T05:52:19ZengWileyCase Reports in Orthopedics2090-67492090-67572019-01-01201910.1155/2019/90246439024643Regeneration of the Fibula with Unidirectional Porous HydroxyapatiteKoji Demiya0Toshiyuki Kunisada1Eiji Nakata2Joe Hasei3Toshifumi Ozaki4Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, JapanDepartment of Medical Materials for Musculoskeletal Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, JapanDepartment of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, JapanDepartment of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, JapanDepartment of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, JapanA fibula graft is one of the most common orthopedic procedures for reconstruction of a bone defect, and some complications related to persistent defects of the fibula have been reported previously. We believe that regeneration of the fibula may be critical for postoperative function and prevention of complications. This report describes a 9-year-old female with Ewing sarcoma of the pelvis who was treated with the double-barrel fibula grafts for pelvic bone defect following tumor resection. The defect after fibular resection was filled with unidirectional porous hydroxyapatite (UDPHAp) implants. A plain radiograph revealed new bone formation and a callus-like structure at one month after surgery and bony union between each UDPHAp implant 5 months after surgery. Resorption of implanted UDPHAp was identified, and partial remodeling of the bone marrow cavity could be seen 1 year 2 months after surgery. A radiograph at final follow-up (5 years 10 months after surgery) demonstrated almost complete absorption of the implanted UDPHAp and clear formation of the cortex and bone marrow in the resected part of the fibula. The patient is able to walk well without any walking supports and to take part in sports activities.http://dx.doi.org/10.1155/2019/9024643 |
| spellingShingle | Koji Demiya Toshiyuki Kunisada Eiji Nakata Joe Hasei Toshifumi Ozaki Regeneration of the Fibula with Unidirectional Porous Hydroxyapatite Case Reports in Orthopedics |
| title | Regeneration of the Fibula with Unidirectional Porous Hydroxyapatite |
| title_full | Regeneration of the Fibula with Unidirectional Porous Hydroxyapatite |
| title_fullStr | Regeneration of the Fibula with Unidirectional Porous Hydroxyapatite |
| title_full_unstemmed | Regeneration of the Fibula with Unidirectional Porous Hydroxyapatite |
| title_short | Regeneration of the Fibula with Unidirectional Porous Hydroxyapatite |
| title_sort | regeneration of the fibula with unidirectional porous hydroxyapatite |
| url | http://dx.doi.org/10.1155/2019/9024643 |
| work_keys_str_mv | AT kojidemiya regenerationofthefibulawithunidirectionalporoushydroxyapatite AT toshiyukikunisada regenerationofthefibulawithunidirectionalporoushydroxyapatite AT eijinakata regenerationofthefibulawithunidirectionalporoushydroxyapatite AT joehasei regenerationofthefibulawithunidirectionalporoushydroxyapatite AT toshifumiozaki regenerationofthefibulawithunidirectionalporoushydroxyapatite |