Optimizing magnetic hyperthermia for melanoma: the role of nanoparticle uptake inhibition

Optimizing magnetic hyperthermia for melanoma: the role of nanoparticle uptake inhibition

Superparamagnetic iron oxide nanoparticles (SPIONs) are widely used in magnetic hyperthermia, where their therapeutic efficacy depends on efficient heat generation. However, intracellular uptake of SPIONs has been shown to reduce their heat dissipation capacity, limiting hyperthermia performance. To...

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Bibliographic Details
Main Authors: Beatriz T Simões, Catarina Chaparro, Tânia Vieira, Manuel A Valente, Marco C V Cavaco, Vera Neves, Jorge C Silva, João Paulo Borges, Filipe V Almeida, Paula Soares
Format: Article
Language:English
Published: IOP Publishing 2025-01-01
Series:Nano Express
Subjects:
iron oxide nanoparticles
magnetic hyperthermia
melanoma cells
small-molecule inhibitors
Online Access:https://doi.org/10.1088/2632-959X/adbde1
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