Efficacy and safety of pegylated interferon in the treatment of JAK2V617F-positive polycythemia vera with a dose de-escalation strategy: a single-center retrospective study

Efficacy and safety of pegylated interferon in the treatment of JAK2V617F-positive polycythemia vera with a dose de-escalation strategy: a single-center retrospective study

IntroductionAlthough pegylated interferon (PEG-IFN) has been widely used in the treatment of polycythemia vera (PV), there is still a significant variability in its specific dosage and administration.MethodsThis single-center retrospective study assessed the efficacy and safety of PEG-IFN in JAK2V61...

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Bibliographic Details
Main Authors: Long Chang, Wen-Xin Li, Hao Cai, Jian Li, Ming-Hui Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
polycythemia vera
pegylated interferon
JAK2v617F mutation
dose de-escalation strategy
hematological and molecular response
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1586839/full
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