Tiantan vaccinia virus-based vaccine with promising safety provides sustained protection against mpox in non-human primates

Tiantan vaccinia virus-based vaccine with promising safety provides sustained protection against mpox in non-human primates

Abstract The World Health Organization (WHO) has declared the mpox outbreak a public health emergency of international concern (PHEIC). Safe and efficient vaccines against the mpox virus (MPXV) are urgently needed to impede the surge in cases. Here, we report the results of a preclinical study emplo...

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Main Authors: Lin Zhu, Shuyuan Pan, Baoying Huang, Junjie Zhang, Zhaona Yang, Zhe Cong, Jianrong Ma, Shaoting Qiu, Yang Liu, Jingjing Zhang, Na Li, Jiahan Lu, Ting Chen, Yongzhi Hou, Dong Zhang, Qiang Wei, Dan Li, Wenjie Tan, Yuntao Zhang, Jing Xue
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62594-0
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https://doi.org/10.1038/s41467-025-62594-0

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