Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature Analysis
<b>Background/Objectives</b>: Odontogenic tumors in pediatric patients are uncommon; among all, the intraosseous occurrence of odontogenic myxoma is very rare, accounting for almost 8.5–11.6% of all odontogenic tumors in children. The radiological appearance is highly variable and is oft...
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MDPI AG
2025-01-01
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| Online Access: | https://www.mdpi.com/2227-9067/12/2/158 |
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| author | Marta Forte Giuseppe D’Albis Antonio d’Amati Giuseppe Ingravallo Luisa Limongelli Gianfranco Favia Adriano Di Grigoli Anna Montaruli Daniela Di Venere Massimo Corsalini Saverio Capodiferro |
| author_facet | Marta Forte Giuseppe D’Albis Antonio d’Amati Giuseppe Ingravallo Luisa Limongelli Gianfranco Favia Adriano Di Grigoli Anna Montaruli Daniela Di Venere Massimo Corsalini Saverio Capodiferro |
| author_sort | Marta Forte |
| collection | DOAJ |
| description | <b>Background/Objectives</b>: Odontogenic tumors in pediatric patients are uncommon; among all, the intraosseous occurrence of odontogenic myxoma is very rare, accounting for almost 8.5–11.6% of all odontogenic tumors in children. The radiological appearance is highly variable and is often responsible for the diagnostic delay and treatment. <b>Methods</b>: We report a case of odontogenic myxoma occurring in the posterior mandible of a 12-year-old female, found on a panoramic radiograph performed for the delayed eruption of the second inferior molar, treated by conservative surgery. A comprehensive analysis of the literature was also carried out. <b>Results</b>: The radiological features of the presented case were unique, as the lesion was encompassed within the uncompleted (developing) dental crown still unerupted, as confirmed by the macroscopic appearance. Then, the differential diagnosis included odontogenic fibroma, immature dental pulp or follicle from a developing tooth, and ameloblastic fibrodontoma. The histological examination led to the final diagnosis of odontogenic myxoma. As for the literature analysis, after a PRISMA-based selection of the papers, a total of 23 articles (case reports and case series on odontogenic myxomas in pediatric patients, a total of 33 cases) were finally selected and studied; all the pertinent data are widely discussed within the paper. <b>Conclusions</b>: The current case highlights the importance of the radiological investigation in pediatric patients when a delayed eruption lasts for several months, leading to an early diagnosis necessary to avoid more aggressive surgical therapies and possible recurrence; data from the literature about site of occurrence, sex, age, kind of surgical procedure, and recurrence rate are discussed too. |
| format | Article |
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| institution | DOAJ |
| issn | 2227-9067 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj-art-3b4e04bb84db49df9ce67fa5babb62c02025-08-20T03:12:11ZengMDPI AGChildren2227-90672025-01-0112215810.3390/children12020158Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature AnalysisMarta Forte0Giuseppe D’Albis1Antonio d’Amati2Giuseppe Ingravallo3Luisa Limongelli4Gianfranco Favia5Adriano Di Grigoli6Anna Montaruli7Daniela Di Venere8Massimo Corsalini9Saverio Capodiferro10Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, ItalyDepartment of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70100 Bari, Italy<b>Background/Objectives</b>: Odontogenic tumors in pediatric patients are uncommon; among all, the intraosseous occurrence of odontogenic myxoma is very rare, accounting for almost 8.5–11.6% of all odontogenic tumors in children. The radiological appearance is highly variable and is often responsible for the diagnostic delay and treatment. <b>Methods</b>: We report a case of odontogenic myxoma occurring in the posterior mandible of a 12-year-old female, found on a panoramic radiograph performed for the delayed eruption of the second inferior molar, treated by conservative surgery. A comprehensive analysis of the literature was also carried out. <b>Results</b>: The radiological features of the presented case were unique, as the lesion was encompassed within the uncompleted (developing) dental crown still unerupted, as confirmed by the macroscopic appearance. Then, the differential diagnosis included odontogenic fibroma, immature dental pulp or follicle from a developing tooth, and ameloblastic fibrodontoma. The histological examination led to the final diagnosis of odontogenic myxoma. As for the literature analysis, after a PRISMA-based selection of the papers, a total of 23 articles (case reports and case series on odontogenic myxomas in pediatric patients, a total of 33 cases) were finally selected and studied; all the pertinent data are widely discussed within the paper. <b>Conclusions</b>: The current case highlights the importance of the radiological investigation in pediatric patients when a delayed eruption lasts for several months, leading to an early diagnosis necessary to avoid more aggressive surgical therapies and possible recurrence; data from the literature about site of occurrence, sex, age, kind of surgical procedure, and recurrence rate are discussed too.https://www.mdpi.com/2227-9067/12/2/158odontogenic tumorsodontogenic myxomamandibleretained toothpediatric patient |
| spellingShingle | Marta Forte Giuseppe D’Albis Antonio d’Amati Giuseppe Ingravallo Luisa Limongelli Gianfranco Favia Adriano Di Grigoli Anna Montaruli Daniela Di Venere Massimo Corsalini Saverio Capodiferro Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature Analysis Children odontogenic tumors odontogenic myxoma mandible retained tooth pediatric patient |
| title | Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature Analysis |
| title_full | Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature Analysis |
| title_fullStr | Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature Analysis |
| title_full_unstemmed | Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature Analysis |
| title_short | Odontogenic Myxoma Associated to Unerupted Mandibular Molar in a Pediatric Patient: A New Case Description with Comprehensive Literature Analysis |
| title_sort | odontogenic myxoma associated to unerupted mandibular molar in a pediatric patient a new case description with comprehensive literature analysis |
| topic | odontogenic tumors odontogenic myxoma mandible retained tooth pediatric patient |
| url | https://www.mdpi.com/2227-9067/12/2/158 |
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