From Pregnancy to Postpartum: The Dynamic Reorganization of the Maternal Brain

The postpartum period is marked by radical changes in the maternal brain. Seeking to explore the mechanisms that underlie these changes, this article focuses on the relevant hormonal, inflammatory, and behavioral factors. Longitudinal imaging studies have shed valuable light on both short- and long-...

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Main Authors: Natalia Chechko, Susanne Nehls
Format: Article
Language:English
Published: SAGE Publishing 2025-01-01
Series:Neuroscience Insights
Online Access:https://doi.org/10.1177/26331055251315488
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author Natalia Chechko
Susanne Nehls
author_facet Natalia Chechko
Susanne Nehls
author_sort Natalia Chechko
collection DOAJ
description The postpartum period is marked by radical changes in the maternal brain. Seeking to explore the mechanisms that underlie these changes, this article focuses on the relevant hormonal, inflammatory, and behavioral factors. Longitudinal imaging studies have shed valuable light on both short- and long-term alterations in postpartum brain structure and connectivity, particularly in the regions that play key roles in emotion regulation and stress response. It is plausible that these peripartum changes contribute to the mental health challenges new mothers face, including postpartum depression. Adding to our understanding of postpartum neurobiology, this insight highlights the importance of personalized intervention in the promotion of maternal well-being.
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spelling doaj-art-3b3db3458bc246609eedc7b4e74720d02025-01-20T06:03:19ZengSAGE PublishingNeuroscience Insights2633-10552025-01-012010.1177/26331055251315488From Pregnancy to Postpartum: The Dynamic Reorganization of the Maternal BrainNatalia Chechko0Susanne Nehls1Institute of Neuroscience and Medicine, Brain and Behavior (INM-7), Research Center Jülich, Jülich, GermanyInstitute of Neuroscience and Medicine, JARA-Institute Brain Structure Function Relationship (INM 10), Research Center Jülich, Jülich, GermanyThe postpartum period is marked by radical changes in the maternal brain. Seeking to explore the mechanisms that underlie these changes, this article focuses on the relevant hormonal, inflammatory, and behavioral factors. Longitudinal imaging studies have shed valuable light on both short- and long-term alterations in postpartum brain structure and connectivity, particularly in the regions that play key roles in emotion regulation and stress response. It is plausible that these peripartum changes contribute to the mental health challenges new mothers face, including postpartum depression. Adding to our understanding of postpartum neurobiology, this insight highlights the importance of personalized intervention in the promotion of maternal well-being.https://doi.org/10.1177/26331055251315488
spellingShingle Natalia Chechko
Susanne Nehls
From Pregnancy to Postpartum: The Dynamic Reorganization of the Maternal Brain
Neuroscience Insights
title From Pregnancy to Postpartum: The Dynamic Reorganization of the Maternal Brain
title_full From Pregnancy to Postpartum: The Dynamic Reorganization of the Maternal Brain
title_fullStr From Pregnancy to Postpartum: The Dynamic Reorganization of the Maternal Brain
title_full_unstemmed From Pregnancy to Postpartum: The Dynamic Reorganization of the Maternal Brain
title_short From Pregnancy to Postpartum: The Dynamic Reorganization of the Maternal Brain
title_sort from pregnancy to postpartum the dynamic reorganization of the maternal brain
url https://doi.org/10.1177/26331055251315488
work_keys_str_mv AT nataliachechko frompregnancytopostpartumthedynamicreorganizationofthematernalbrain
AT susannenehls frompregnancytopostpartumthedynamicreorganizationofthematernalbrain