Exploring the Role of Oleic Acid in Muscle Cell Differentiation: Mechanisms and Implications for Myogenesis and Metabolic Regulation in C2C12 Myoblasts

Exploring the Role of Oleic Acid in Muscle Cell Differentiation: Mechanisms and Implications for Myogenesis and Metabolic Regulation in C2C12 Myoblasts

<b>Background/Objectives</b>: Myogenesis, the process by which myoblasts differentiate into multinucleated muscle fibers, is tightly regulated by transcription factors, signaling pathways, and metabolic cues. Among these, fatty acids have emerged as key regulators beyond their traditiona...

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Bibliographic Details
Main Authors: Francesco Vari, Elisa Bisconti, Ilaria Serra, Eleonora Stanca, Marzia Friuli, Daniele Vergara, Anna Maria Giudetti
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
C2C12 myoblast differentiation
glucose uptake
lipid droplets
oleic acid
skeletal muscle
Online Access:https://www.mdpi.com/2227-9059/13/7/1568
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