Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formula

Abstract Background Bisphenol A (BPA) is one of the chemical compounds used in food packaging, so it can migrate from the packaging into food. Also, environmental pollution of this compound is high due to its high use. Therefore, it may enter food chains through the environment. Aflatoxin M1 (AFM1)...

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Main Authors: Ghazal Mirzaei, Najmeh Yazdanfar, Nabi Shariatifar, Ebrahim Molaee -Aghaee, Parisa Sadighara
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Nutrition
Subjects:
Online Access:https://doi.org/10.1186/s40795-025-00998-3
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author Ghazal Mirzaei
Najmeh Yazdanfar
Nabi Shariatifar
Ebrahim Molaee -Aghaee
Parisa Sadighara
author_facet Ghazal Mirzaei
Najmeh Yazdanfar
Nabi Shariatifar
Ebrahim Molaee -Aghaee
Parisa Sadighara
author_sort Ghazal Mirzaei
collection DOAJ
description Abstract Background Bisphenol A (BPA) is one of the chemical compounds used in food packaging, so it can migrate from the packaging into food. Also, environmental pollution of this compound is high due to its high use. Therefore, it may enter food chains through the environment. Aflatoxin M1 (AFM1) is one of the common mycotoxins in milk. Its presence has been reported worldwide. Infant formula is an alternative to human milk. The main ingredient of this product is cow’s milk. Aims This study aimed to investigate the levels and risk assessment of BPA and aflatoxin M1 in infant formula. Methods Samples were purchased from 7 leading brands of infant formula in pharmacies. The samples were extracted according to common protocols and then injected into HPLC and analyzed with a fluorescence detector for both contaminants. Results BPA wasn’t detected in infant formula samples, but the presence of AFM1was confirmed in 11% of the samples. Of course, there is no risk in this regard with the risk assessment. Conclusion Infant formula samples are not of concern for infants in terms of BPA and aflatoxin M1. However, continuous monitoring is recommended for this product.
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institution Kabale University
issn 2055-0928
language English
publishDate 2025-01-01
publisher BMC
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series BMC Nutrition
spelling doaj-art-3b11072f33be4465b44eb101076000062025-01-19T12:13:18ZengBMCBMC Nutrition2055-09282025-01-011111610.1186/s40795-025-00998-3Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formulaGhazal Mirzaei0Najmeh Yazdanfar1Nabi Shariatifar2Ebrahim Molaee -Aghaee3Parisa Sadighara4Department of Environmental Health Engineering, Division of Food Safety and Hygiene, School of public health, Tehran University of Medical SciencesIranian Research and Development Center for Chemical Industries, ACECRDepartment of Environmental Health Engineering, Division of Food Safety and Hygiene, School of public health, Tehran University of Medical SciencesDepartment of Environmental Health Engineering, Division of Food Safety and Hygiene, School of public health, Tehran University of Medical SciencesDepartment of Environmental Health Engineering, Division of Food Safety and Hygiene, School of public health, Tehran University of Medical SciencesAbstract Background Bisphenol A (BPA) is one of the chemical compounds used in food packaging, so it can migrate from the packaging into food. Also, environmental pollution of this compound is high due to its high use. Therefore, it may enter food chains through the environment. Aflatoxin M1 (AFM1) is one of the common mycotoxins in milk. Its presence has been reported worldwide. Infant formula is an alternative to human milk. The main ingredient of this product is cow’s milk. Aims This study aimed to investigate the levels and risk assessment of BPA and aflatoxin M1 in infant formula. Methods Samples were purchased from 7 leading brands of infant formula in pharmacies. The samples were extracted according to common protocols and then injected into HPLC and analyzed with a fluorescence detector for both contaminants. Results BPA wasn’t detected in infant formula samples, but the presence of AFM1was confirmed in 11% of the samples. Of course, there is no risk in this regard with the risk assessment. Conclusion Infant formula samples are not of concern for infants in terms of BPA and aflatoxin M1. However, continuous monitoring is recommended for this product.https://doi.org/10.1186/s40795-025-00998-3Bisphenol AAflatoxin M1Infant formulaHPLCFood packagingEnvironmental pollution
spellingShingle Ghazal Mirzaei
Najmeh Yazdanfar
Nabi Shariatifar
Ebrahim Molaee -Aghaee
Parisa Sadighara
Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formula
BMC Nutrition
Bisphenol A
Aflatoxin M1
Infant formula
HPLC
Food packaging
Environmental pollution
title Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formula
title_full Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formula
title_fullStr Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formula
title_full_unstemmed Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formula
title_short Health risk assessment and determination of bisphenol A and aflatoxin M1 in infant formula
title_sort health risk assessment and determination of bisphenol a and aflatoxin m1 in infant formula
topic Bisphenol A
Aflatoxin M1
Infant formula
HPLC
Food packaging
Environmental pollution
url https://doi.org/10.1186/s40795-025-00998-3
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AT najmehyazdanfar healthriskassessmentanddeterminationofbisphenolaandaflatoxinm1ininfantformula
AT nabishariatifar healthriskassessmentanddeterminationofbisphenolaandaflatoxinm1ininfantformula
AT ebrahimmolaeeaghaee healthriskassessmentanddeterminationofbisphenolaandaflatoxinm1ininfantformula
AT parisasadighara healthriskassessmentanddeterminationofbisphenolaandaflatoxinm1ininfantformula