Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway
Background: Neuronal cholesterol deficiency may contribute to the synaptopathy observed in Alzheimer’s disease (AD). However, the underlying mechanisms remain poorly understood. Intact synaptic vesicle (SV) mobility is crucial for normal synaptic function, whereas disrupted SV mob...
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Main Authors: | Atikam Qurban, Mengqi Zhang, Hengbing Zu, Kai Yao |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2025-01-01
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Series: | Frontiers in Bioscience-Landmark |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/FBL/30/1/10.31083/FBL27111 |
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