Androgen Deprivation Therapy Toxicity and Management for Men Receiving Radiation Therapy

Androgen deprivation therapy is commonly used in combination with radiotherapy as part of the definitive treatment for men with clinically localized and locally advanced prostate cancer. Androgen deprivation has been associated with a wide range of iatrogenic effects impacting a variety of body sys...

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Main Authors: Matthew E. Johnson, Mark K. Buyyounouski
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2012/580306
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author Matthew E. Johnson
Mark K. Buyyounouski
author_facet Matthew E. Johnson
Mark K. Buyyounouski
author_sort Matthew E. Johnson
collection DOAJ
description Androgen deprivation therapy is commonly used in combination with radiotherapy as part of the definitive treatment for men with clinically localized and locally advanced prostate cancer. Androgen deprivation has been associated with a wide range of iatrogenic effects impacting a variety of body systems including metabolic, musculoskeletal, cardiovascular, neurocognitive, and sexual. This review aims to provide the radiation oncology community with the knowledge to monitor and manage androgen deprivation therapy toxicity in an effort to provide the highest level of care for patients and to minimize the iatrogenic effects of androgen deprivation as much as possible.
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spelling doaj-art-3b09b062e9b34e108d91b482f738500a2025-02-03T01:21:44ZengWileyProstate Cancer2090-31112090-312X2012-01-01201210.1155/2012/580306580306Androgen Deprivation Therapy Toxicity and Management for Men Receiving Radiation TherapyMatthew E. Johnson0Mark K. Buyyounouski1Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USADepartment of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USAAndrogen deprivation therapy is commonly used in combination with radiotherapy as part of the definitive treatment for men with clinically localized and locally advanced prostate cancer. Androgen deprivation has been associated with a wide range of iatrogenic effects impacting a variety of body systems including metabolic, musculoskeletal, cardiovascular, neurocognitive, and sexual. This review aims to provide the radiation oncology community with the knowledge to monitor and manage androgen deprivation therapy toxicity in an effort to provide the highest level of care for patients and to minimize the iatrogenic effects of androgen deprivation as much as possible.http://dx.doi.org/10.1155/2012/580306
spellingShingle Matthew E. Johnson
Mark K. Buyyounouski
Androgen Deprivation Therapy Toxicity and Management for Men Receiving Radiation Therapy
Prostate Cancer
title Androgen Deprivation Therapy Toxicity and Management for Men Receiving Radiation Therapy
title_full Androgen Deprivation Therapy Toxicity and Management for Men Receiving Radiation Therapy
title_fullStr Androgen Deprivation Therapy Toxicity and Management for Men Receiving Radiation Therapy
title_full_unstemmed Androgen Deprivation Therapy Toxicity and Management for Men Receiving Radiation Therapy
title_short Androgen Deprivation Therapy Toxicity and Management for Men Receiving Radiation Therapy
title_sort androgen deprivation therapy toxicity and management for men receiving radiation therapy
url http://dx.doi.org/10.1155/2012/580306
work_keys_str_mv AT matthewejohnson androgendeprivationtherapytoxicityandmanagementformenreceivingradiationtherapy
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