From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine Colic

Colic is a leading cause of mortality in horses, demanding precise and timely interventions. This study integrates machine learning and explainable artificial intelligence (XAI) to predict survival outcomes in horses with colic, using clinical, procedural, and diagnostic data. Random forest and XGBo...

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Main Authors: Bekir Cetintav, Ahmet Yalcin
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/15/2/126
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author Bekir Cetintav
Ahmet Yalcin
author_facet Bekir Cetintav
Ahmet Yalcin
author_sort Bekir Cetintav
collection DOAJ
description Colic is a leading cause of mortality in horses, demanding precise and timely interventions. This study integrates machine learning and explainable artificial intelligence (XAI) to predict survival outcomes in horses with colic, using clinical, procedural, and diagnostic data. Random forest and XGBoost emerged as top-performing models, achieving F1 scores of 85.9% and 86.1%, respectively. SHAP (Shapley additive explanations) was employed to provide interpretable insights, offering both global and local explanations for model predictions. The analysis revealed that key features, such as pulse rate, lesion type, and total protein levels, significantly influenced survival likelihood. Local interpretations highlighted the unique contribution of clinical factors to individual cases, enabling personalized insights that guide targeted treatment strategies. These tailored predictions empower veterinarians to prioritize interventions based on the specific conditions of each horse, moving beyond generalized care protocols. By combining predictive accuracy with interpretability, this study advances precision veterinary medicine, enhancing outcomes for equine colic cases and setting a benchmark for future applications of AI in animal health.
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institution Kabale University
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spelling doaj-art-3af89fe1861547388b17f99f409571362025-01-24T13:17:40ZengMDPI AGAnimals2076-26152025-01-0115212610.3390/ani15020126From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine ColicBekir Cetintav0Ahmet Yalcin1Department of Biostatistics, Veterinary Faculty, Burdur Mehmet Akif Ersoy University, 15030 Burdur Merkez, TurkeyInstitute of Science, Burdur Mehmet Akif Ersoy University, 15030 Burdur Merkez, TurkeyColic is a leading cause of mortality in horses, demanding precise and timely interventions. This study integrates machine learning and explainable artificial intelligence (XAI) to predict survival outcomes in horses with colic, using clinical, procedural, and diagnostic data. Random forest and XGBoost emerged as top-performing models, achieving F1 scores of 85.9% and 86.1%, respectively. SHAP (Shapley additive explanations) was employed to provide interpretable insights, offering both global and local explanations for model predictions. The analysis revealed that key features, such as pulse rate, lesion type, and total protein levels, significantly influenced survival likelihood. Local interpretations highlighted the unique contribution of clinical factors to individual cases, enabling personalized insights that guide targeted treatment strategies. These tailored predictions empower veterinarians to prioritize interventions based on the specific conditions of each horse, moving beyond generalized care protocols. By combining predictive accuracy with interpretability, this study advances precision veterinary medicine, enhancing outcomes for equine colic cases and setting a benchmark for future applications of AI in animal health.https://www.mdpi.com/2076-2615/15/2/126equine colicexplainable artificial intelligence (XAI)machine learning in veterinary medicineSHAPprecision animal health managementtargeted veterinary medicine
spellingShingle Bekir Cetintav
Ahmet Yalcin
From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine Colic
Animals
equine colic
explainable artificial intelligence (XAI)
machine learning in veterinary medicine
SHAP
precision animal health management
targeted veterinary medicine
title From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine Colic
title_full From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine Colic
title_fullStr From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine Colic
title_full_unstemmed From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine Colic
title_short From Prediction to Precision: Explainable AI-Driven Insights for Targeted Treatment in Equine Colic
title_sort from prediction to precision explainable ai driven insights for targeted treatment in equine colic
topic equine colic
explainable artificial intelligence (XAI)
machine learning in veterinary medicine
SHAP
precision animal health management
targeted veterinary medicine
url https://www.mdpi.com/2076-2615/15/2/126
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