Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021
Background & Aims: The Ministry of Health and Treatment implemented vaccination as one of the primary strategies to control the coronavirus disease 2019 (COVID-19) pandemic. Given their critical role in treatment and disease control, healthcare workers were prioritized for vaccination. This stu...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Urmia University of Medical Sciences
2025-02-01
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| Series: | Health Science Monitor |
| Subjects: | |
| Online Access: | http://hsm.umsu.ac.ir/article-1-191-en.pdf |
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| Summary: | Background & Aims: The Ministry of Health and Treatment implemented vaccination as one of the primary strategies to control the coronavirus disease 2019 (COVID-19) pandemic. Given their critical role in treatment and disease control, healthcare workers were prioritized for vaccination. This study aims to assess the vaccination status and level of immunity against COVID-19 among healthcare workers at Shahid Motahari Hospital in Urmia, Iran, in 2021.
Materials & Methods: A cross-sectional study was conducted with 150 volunteer healthcare workers at Shahid Motahari Hospital. Venous blood samples were collected to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibodies using the ELISA method. Data analysis was performed using version 16 of SPSS software.
Results: The participants had a mean age of 37.5 years, with 47.3% being male. A significant 98% of the participants were vaccinated against COVID-19. The predominant vaccines administered were Sputnik V (72%), AstraZeneca (54%), and Sinopharm (27%). The mean level of SARS-CoV-2 neutralizing antibodies was significantly higher in vaccinated individuals compared to unvaccinated individuals (p = 0.001). There was no significant difference in antibody levels between male and female participants (p = 0.67). A positive correlation was observed between the number of vaccine doses received and the level of neutralizing antibodies (R = 0.207).
Conclusion: Vaccination with the mentioned vaccines, whether administered singly or in combination, effectively increased serum antibody levels, providing sufficient protection against COVID-19 for healthcare workers. To maintain immunity levels among healthcare workers and protect against emerging strains of the virus, it is essential to administer booster doses. |
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| ISSN: | 2980-8723 |