Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature

Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based...

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Main Authors: Majid Alsahafi, Mohammed I. AlJasser, Sunil Kalia, H. M. Yang, Alnoor Ramji
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2017/8768529
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author Majid Alsahafi
Mohammed I. AlJasser
Sunil Kalia
H. M. Yang
Alnoor Ramji
author_facet Majid Alsahafi
Mohammed I. AlJasser
Sunil Kalia
H. M. Yang
Alnoor Ramji
author_sort Majid Alsahafi
collection DOAJ
description Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based on the possible immune pathophysiology of GA and the presence of liver granulomas, the patient was treated with prednisone and azathioprine which resulted in complete normalization of the liver enzymes and concurrent improvement of GA. The association between liver diseases and GA is reviewed.
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institution Kabale University
issn 2090-6528
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language English
publishDate 2017-01-01
publisher Wiley
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-3aef3623e9d24c728a6f7184bd736bdd2025-02-03T06:07:53ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362017-01-01201710.1155/2017/87685298768529Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the LiteratureMajid Alsahafi0Mohammed I. AlJasser1Sunil Kalia2H. M. Yang3Alnoor Ramji4Division of Gastroenterology, University of British Columbia, Vancouver, BC, CanadaDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, CanadaDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, CanadaDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, CanadaDivision of Gastroenterology, University of British Columbia, Vancouver, BC, CanadaGranuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based on the possible immune pathophysiology of GA and the presence of liver granulomas, the patient was treated with prednisone and azathioprine which resulted in complete normalization of the liver enzymes and concurrent improvement of GA. The association between liver diseases and GA is reviewed.http://dx.doi.org/10.1155/2017/8768529
spellingShingle Majid Alsahafi
Mohammed I. AlJasser
Sunil Kalia
H. M. Yang
Alnoor Ramji
Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
Case Reports in Gastrointestinal Medicine
title Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_full Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_fullStr Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_full_unstemmed Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_short Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature
title_sort chronic hepatitis with liver granulomas in a patient with granuloma annulare a case report and review of the literature
url http://dx.doi.org/10.1155/2017/8768529
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