Study on the Scale-Up Possibility of a Combined Wet Grinding Technique Intended for Oral Administration of Meloxicam Nanosuspension

Study on the Scale-Up Possibility of a Combined Wet Grinding Technique Intended for Oral Administration of Meloxicam Nanosuspension

<b>Background/Objectives:</b> This article reports on the scalability of a combined wet grinding technique applying planetary ball mill and ZrO<sub>2</sub> pearls as the grinding medium. After the determination of the parameters in a laboratory scale, the tenfold scale-up met...

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Bibliographic Details
Main Authors: Csilla Bartos, Anett Motzwickler-Németh, Dávid Kovács, Katalin Burián, Rita Ambrus
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
Subjects:
combined wet grinding/milling
scale-up method
meloxicam
nanonization
dissolution
cytotoxicity
Online Access:https://www.mdpi.com/1999-4923/16/12/1512
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