Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is a heterogeneous group of lymphoid disorders characterized by monoclonal proliferation and expansion of immature lymphoid cells in the bone marrow, blood, and other organs. It commonly presents with nonspecific symptoms such as lethargy, easy bruising, and weight...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2018/9175360 |
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| _version_ | 1832565013454258176 |
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| author | Oreoluwa Oladiran Ifeanyi Nwosu |
| author_facet | Oreoluwa Oladiran Ifeanyi Nwosu |
| author_sort | Oreoluwa Oladiran |
| collection | DOAJ |
| description | Acute lymphoblastic leukemia (ALL) is a heterogeneous group of lymphoid disorders characterized by monoclonal proliferation and expansion of immature lymphoid cells in the bone marrow, blood, and other organs. It commonly presents with nonspecific symptoms such as lethargy, easy bruising, and weight loss. In this article, we present the case of a 48-year-old male who presented to the hospital with painless jaundice resulting from pancreatic infiltration, initially thought to be due to pancreatic or hepatobiliary malignancy. He was later diagnosed with ALL by lymph node biopsy and peripheral blood flow cytometry immunophenotyping and was transferred to a cancer treatment centre for unilateral bone marrow biopsy and further management. Our case highlights the rare occurrence of pancreatic infiltration in ALL. |
| format | Article |
| id | doaj-art-3ad3a33da38344e89d4ca631b7fbaff5 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-3ad3a33da38344e89d4ca631b7fbaff52025-02-03T01:09:40ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/91753609175360Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic LeukemiaOreoluwa Oladiran0Ifeanyi Nwosu1Reading Hospital, Tower Health System, West Reading, PA, USALeighton Hospital NHS Trust, Crewe, Cheshire, UKAcute lymphoblastic leukemia (ALL) is a heterogeneous group of lymphoid disorders characterized by monoclonal proliferation and expansion of immature lymphoid cells in the bone marrow, blood, and other organs. It commonly presents with nonspecific symptoms such as lethargy, easy bruising, and weight loss. In this article, we present the case of a 48-year-old male who presented to the hospital with painless jaundice resulting from pancreatic infiltration, initially thought to be due to pancreatic or hepatobiliary malignancy. He was later diagnosed with ALL by lymph node biopsy and peripheral blood flow cytometry immunophenotyping and was transferred to a cancer treatment centre for unilateral bone marrow biopsy and further management. Our case highlights the rare occurrence of pancreatic infiltration in ALL.http://dx.doi.org/10.1155/2018/9175360 |
| spellingShingle | Oreoluwa Oladiran Ifeanyi Nwosu Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia Case Reports in Hematology |
| title | Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia |
| title_full | Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia |
| title_fullStr | Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia |
| title_full_unstemmed | Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia |
| title_short | Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia |
| title_sort | obstructive jaundice due to pancreatic involvement as an initial presentation of adult acute lymphoblastic leukemia |
| url | http://dx.doi.org/10.1155/2018/9175360 |
| work_keys_str_mv | AT oreoluwaoladiran obstructivejaundiceduetopancreaticinvolvementasaninitialpresentationofadultacutelymphoblasticleukemia AT ifeanyinwosu obstructivejaundiceduetopancreaticinvolvementasaninitialpresentationofadultacutelymphoblasticleukemia |