ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTS
Background: Inflammation is a normal process in response to injury, but causes problems for the patient, including the appearance of pain, swelling, or fever. Anti-inflammatory agents generally used for those conditions, have several side effects to patients. Purpose: The objective of this research...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2019-01-01
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| Series: | Journal of Vocational Health Studies |
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| Online Access: | https://e-journal.unair.ac.id/JVHS/article/view/11471 |
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| author | Swandari Paramita Muhammad Khairul Nuryanto |
| author_facet | Swandari Paramita Muhammad Khairul Nuryanto |
| author_sort | Swandari Paramita |
| collection | DOAJ |
| description | Background: Inflammation is a normal process in response to injury, but causes problems for the patient, including the appearance of pain, swelling, or fever. Anti-inflammatory agents generally used for those conditions, have several side effects to patients. Purpose: The objective of this research was to find alternative anti-inflammatory agents, especially from natural sources. Eleutherine bulbosa (Mill.) Urb. knew as “Bawang Dayak” belong to family Iridaceae is one of the natural sources for anti-inflammatory agents. This plant is known as traditional medicine in East Kalimantan and used as material in this research. Method: The experimental method of anti-inflammatory measurement using membrane stabilization activity for E. Bulbosa ethanol bulbs extracts. Result: The results showed that significant differences of EC50(p < 0.05) were achieved between indomethacin (26.39 ± 2.91) as the positive control with E. Bulbosa (52.87 ± 2.29). EC50 of E. bulbosa showed the potential anti-inflammatory activities with similar effectiveness to half indomethacin concentration. Conclusion: It could be concluded that E. bulbosa could be further developed as a new natural source of the anti-inflammatory agents. |
| format | Article |
| id | doaj-art-3aaf363b377c4e39b3a335506574fcd2 |
| institution | Kabale University |
| issn | 2580-7161 2580-717X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Journal of Vocational Health Studies |
| spelling | doaj-art-3aaf363b377c4e39b3a335506574fcd22025-02-02T13:03:58ZengUniversitas AirlanggaJournal of Vocational Health Studies2580-71612580-717X2019-01-0122515510.20473/jvhs.V2.I2.2018.51-555753ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTSSwandari Paramita0Muhammad Khairul Nuryanto1Community Medical Science Laboratory, Faculty of Medicine, Universitas Mulawarman, Samarinda, East KalimantanCenter for Drug Research and Development, Research Institution and Community Service, Universitas Mulawarman, Samarinda, East KalimantanBackground: Inflammation is a normal process in response to injury, but causes problems for the patient, including the appearance of pain, swelling, or fever. Anti-inflammatory agents generally used for those conditions, have several side effects to patients. Purpose: The objective of this research was to find alternative anti-inflammatory agents, especially from natural sources. Eleutherine bulbosa (Mill.) Urb. knew as “Bawang Dayak” belong to family Iridaceae is one of the natural sources for anti-inflammatory agents. This plant is known as traditional medicine in East Kalimantan and used as material in this research. Method: The experimental method of anti-inflammatory measurement using membrane stabilization activity for E. Bulbosa ethanol bulbs extracts. Result: The results showed that significant differences of EC50(p < 0.05) were achieved between indomethacin (26.39 ± 2.91) as the positive control with E. Bulbosa (52.87 ± 2.29). EC50 of E. bulbosa showed the potential anti-inflammatory activities with similar effectiveness to half indomethacin concentration. Conclusion: It could be concluded that E. bulbosa could be further developed as a new natural source of the anti-inflammatory agents.https://e-journal.unair.ac.id/JVHS/article/view/11471anti-inflammatoryeleutherinebulbosamembrane stabilization |
| spellingShingle | Swandari Paramita Muhammad Khairul Nuryanto ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTS Journal of Vocational Health Studies anti-inflammatory eleutherinebulbosa membrane stabilization |
| title | ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTS |
| title_full | ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTS |
| title_fullStr | ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTS |
| title_full_unstemmed | ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTS |
| title_short | ANTI-INFLAMMATORY ACTIVITY OF BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL. URB.))ETHANOL BULB EXTRACTS |
| title_sort | anti inflammatory activity of bawang dayak eleutherine bulbosa mill urb ethanol bulb extracts |
| topic | anti-inflammatory eleutherinebulbosa membrane stabilization |
| url | https://e-journal.unair.ac.id/JVHS/article/view/11471 |
| work_keys_str_mv | AT swandariparamita antiinflammatoryactivityofbawangdayakeleutherinebulbosamillurbethanolbulbextracts AT muhammadkhairulnuryanto antiinflammatoryactivityofbawangdayakeleutherinebulbosamillurbethanolbulbextracts |