Controlled human malaria infection: overview and potential application in the evaluation of transmission-blocking interventions in malaria-endemic areas

Abstract Controlled human malaria infection (CHMI) involves the intentional infection of healthy individuals with malaria parasites, close observation of the volunteers, and clearance of the parasite at a predetermined endpoint. Depending on the need, CHMI can be initiated by either sporozoites or t...

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Bibliographic Details
Main Authors: Enock J. Kessy, Ally I. Olotu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Malaria Journal
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Online Access:https://doi.org/10.1186/s12936-025-05277-x
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