Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for Clinicians

The pathogenesis of recurrent urinary tract infections (rUTIs), a common problem in the female population, is becoming better understood following recent studies of bacterial persistence and intracellular bacterial communities. Incorporating these new insights, we propose pulsed antibiotic therapy w...

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Main Authors: Dino Sgarabotto, Elena Andretta, Camilla Sgarabotto
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/14/1/22
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author Dino Sgarabotto
Elena Andretta
Camilla Sgarabotto
author_facet Dino Sgarabotto
Elena Andretta
Camilla Sgarabotto
author_sort Dino Sgarabotto
collection DOAJ
description The pathogenesis of recurrent urinary tract infections (rUTIs), a common problem in the female population, is becoming better understood following recent studies of bacterial persistence and intracellular bacterial communities. Incorporating these new insights, we propose pulsed antibiotic therapy with intracellular activity as a possible treatment for rUTIs.
format Article
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institution Kabale University
issn 2079-6382
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publisher MDPI AG
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series Antibiotics
spelling doaj-art-3a9698cc2fb2450787864d8790a033232025-01-24T13:18:35ZengMDPI AGAntibiotics2079-63822025-01-011412210.3390/antibiotics14010022Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for CliniciansDino Sgarabotto0Elena Andretta1Camilla Sgarabotto2Policlinico di Abano Terme, 35031 Abano Terme, Padova, ItalySpinal Unit, Oras Hospital, 31045 Motta di Livenza, Treviso, ItalyDepartment of Anesthesia and Intensive Care Unit, ULSS6 Euganea, 35013 Cittadella, Padova, ItalyThe pathogenesis of recurrent urinary tract infections (rUTIs), a common problem in the female population, is becoming better understood following recent studies of bacterial persistence and intracellular bacterial communities. Incorporating these new insights, we propose pulsed antibiotic therapy with intracellular activity as a possible treatment for rUTIs.https://www.mdpi.com/2079-6382/14/1/22recurrent urinary tract infections (UTIs)bacterial persistenceintracellular bacterial communities (IBCs)pulsed antibiotic therapyintracellular active antibiotics
spellingShingle Dino Sgarabotto
Elena Andretta
Camilla Sgarabotto
Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for Clinicians
Antibiotics
recurrent urinary tract infections (UTIs)
bacterial persistence
intracellular bacterial communities (IBCs)
pulsed antibiotic therapy
intracellular active antibiotics
title Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for Clinicians
title_full Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for Clinicians
title_fullStr Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for Clinicians
title_full_unstemmed Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for Clinicians
title_short Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for Clinicians
title_sort recurrent urinary tract infections utis a review and proposal for clinicians
topic recurrent urinary tract infections (UTIs)
bacterial persistence
intracellular bacterial communities (IBCs)
pulsed antibiotic therapy
intracellular active antibiotics
url https://www.mdpi.com/2079-6382/14/1/22
work_keys_str_mv AT dinosgarabotto recurrenturinarytractinfectionsutisareviewandproposalforclinicians
AT elenaandretta recurrenturinarytractinfectionsutisareviewandproposalforclinicians
AT camillasgarabotto recurrenturinarytractinfectionsutisareviewandproposalforclinicians