Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations
Background. Microemboli are a widely recognized etiological factor of cerebral complications in cardiac surgery patients. The present study was aimed to determine if size of left cardiac chambers relates to cerebral microembolic load in open heart operations. Methods. Thirty patients participated in...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.4061/2010/143679 |
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| author | Elena Z. Golukhova Anna G. Polunina Svetlana V. Zhuravleva Natalia P. Lefterova Alexey V. Begachev |
| author_facet | Elena Z. Golukhova Anna G. Polunina Svetlana V. Zhuravleva Natalia P. Lefterova Alexey V. Begachev |
| author_sort | Elena Z. Golukhova |
| collection | DOAJ |
| description | Background. Microemboli are a widely recognized etiological factor of cerebral complications in cardiac surgery patients. The present study was aimed to determine if size of left cardiac chambers relates to cerebral microembolic load in open heart operations. Methods. Thirty patients participated in the study. Echocardiography was performed in 2-3 days before surgery. A transcranial Doppler system was used for registering intraoperative microemboli. Results. Preoperative left atrium and left ventricular end-systolic and end-diastolic sizes significantly correlated with intraoperative microembolic load (𝑟s=0.48, 0.57 and 0.53, 𝑃s≺.01, resp.). The associations between left ventricular diameters and number of cerebral microemboli remained significant when cardiopulmonary bypass time was included as a covariate into the analysis. Conclusions. The present results demonstrate that increased size of left heart chambers is an influential risk factor for elevated cerebral microembolic load during open heart operations. Mini-invasive surgery and carbon dioxide insufflation into wound cavity may be considered as neuroprotective approaches in patients with high risk of cerebral microembolism. |
| format | Article |
| id | doaj-art-3a8dfee07207477aacbf20ee5bb06752 |
| institution | Kabale University |
| issn | 2090-0597 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-3a8dfee07207477aacbf20ee5bb067522025-02-03T01:12:58ZengWileyCardiology Research and Practice2090-05972010-01-01201010.4061/2010/143679143679Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart OperationsElena Z. Golukhova0Anna G. Polunina1Svetlana V. Zhuravleva2Natalia P. Lefterova3Alexey V. Begachev4A. N. Bakulev Scientific Center of Cardiovascular Surgery, Russian Academy of Medical Sciences, Moscow 119571, RussiaA. N. Bakulev Scientific Center of Cardiovascular Surgery, Russian Academy of Medical Sciences, Moscow 119571, RussiaA. N. Bakulev Scientific Center of Cardiovascular Surgery, Russian Academy of Medical Sciences, Moscow 119571, RussiaA. N. Bakulev Scientific Center of Cardiovascular Surgery, Russian Academy of Medical Sciences, Moscow 119571, RussiaAnaesthesiology and Intensive Care Department, Medical Center of the State Bank of Russia, Moscow 117593, RussiaBackground. Microemboli are a widely recognized etiological factor of cerebral complications in cardiac surgery patients. The present study was aimed to determine if size of left cardiac chambers relates to cerebral microembolic load in open heart operations. Methods. Thirty patients participated in the study. Echocardiography was performed in 2-3 days before surgery. A transcranial Doppler system was used for registering intraoperative microemboli. Results. Preoperative left atrium and left ventricular end-systolic and end-diastolic sizes significantly correlated with intraoperative microembolic load (𝑟s=0.48, 0.57 and 0.53, 𝑃s≺.01, resp.). The associations between left ventricular diameters and number of cerebral microemboli remained significant when cardiopulmonary bypass time was included as a covariate into the analysis. Conclusions. The present results demonstrate that increased size of left heart chambers is an influential risk factor for elevated cerebral microembolic load during open heart operations. Mini-invasive surgery and carbon dioxide insufflation into wound cavity may be considered as neuroprotective approaches in patients with high risk of cerebral microembolism.http://dx.doi.org/10.4061/2010/143679 |
| spellingShingle | Elena Z. Golukhova Anna G. Polunina Svetlana V. Zhuravleva Natalia P. Lefterova Alexey V. Begachev Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations Cardiology Research and Practice |
| title | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
| title_full | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
| title_fullStr | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
| title_full_unstemmed | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
| title_short | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
| title_sort | size of left cardiac chambers correlates with cerebral microembolic load in open heart operations |
| url | http://dx.doi.org/10.4061/2010/143679 |
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