The Association Between the Presence of Human Facial Mites Demodex (Acari, Demodicidae) and Dermatological Symptoms in Rosacea Patients in Central Anatolia, Türkiye
Objective: This study aimed to investigate the potential relationship between the presence of Demodex mites and dermatological symptoms in patients with rosacea in the Central Anatolian Region of Türkiye. Methods: A total of 63 patients diagnosed with rosacea were enrolled in the study. Skin sample...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2024-12-01
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| Series: | Türkiye Parazitoloji Dergisi |
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| Online Access: | https://www.turkiyeparazitolderg.org/articles/the-association-between-the-presence-of-human-facial-mites-lessemgreaterdemodex-lessemgreateracari-demodicidae-and-dermatological-symptoms-in-rosacea-patients-in-central-anatolia-turkiye/doi/tpd.galenos.2025.14632 |
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| author | Merve Kahraman Zübeyda Akın Polat Mustafa Esen Feride Çoban Gül |
| author_facet | Merve Kahraman Zübeyda Akın Polat Mustafa Esen Feride Çoban Gül |
| author_sort | Merve Kahraman |
| collection | DOAJ |
| description | Objective: This study aimed to investigate the potential relationship between the presence of Demodex mites and dermatological symptoms in patients with rosacea in the Central Anatolian Region of Türkiye.
Methods: A total of 63 patients diagnosed with rosacea were enrolled in the study. Skin samples were obtained using a standardized skin surface biopsy technique, and a questionnaire was administered to assess skin symptoms. Statistical analysis was performed to evaluate the association between Demodex infestation and specific skin symptoms.
Results: Among the study participants, 65.1% exhibited Demodex infestation. Statistical analysis revealed significant associations between the presence of Demodex and skin burning (p=0.018), skin pain (p=0.012), and skin stinging (p=0.001). However, no statistically significant associations were observed between Demodex presence and gender, skin dryness, itching, irritation, skin rash or the presence of red/pink bumps on the skin.
Conclusion: This study provides evidence suggesting a potential role for Demodex mites in the pathogenesis of rosacea, specifically in relation to skin symptoms such as burning, pain, and stinging. The findings underscore the complexity of the relationship between Demodex infestation and rosacea and highlight the need for further research, including longitudinal and mechanistic studies, to better understand this association and its clinical implications. Ultimately, understanding the role of Demodex mites in rosacea may lead to innovative therapeutic approaches, offering hope for improved management of this challenging dermatological condition. |
| format | Article |
| id | doaj-art-3a7e3ca8b2d14131ba5077a741aae397 |
| institution | Kabale University |
| issn | 1300-6320 2146-3077 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türkiye Parazitoloji Dergisi |
| spelling | doaj-art-3a7e3ca8b2d14131ba5077a741aae3972025-01-23T07:53:18ZengGalenos YayineviTürkiye Parazitoloji Dergisi1300-63202146-30772024-12-0148424024410.4274/tpd.galenos.2025.14632The Association Between the Presence of Human Facial Mites Demodex (Acari, Demodicidae) and Dermatological Symptoms in Rosacea Patients in Central Anatolia, TürkiyeMerve Kahraman0https://orcid.org/0000-0001-7942-9595Zübeyda Akın Polat1https://orcid.org/0000-0002-1130-4953Mustafa Esen2https://orcid.org/0000-0002-1130-4953Feride Çoban Gül3https://orcid.org/0000-0002-3302-0441Sivas Cumhuriyet University Faculty of Medicine, Department of Parasitology, Sivas, TürkiyeSivas Cumhuriyet University Faculty of Medicine, Department of Parasitology, Sivas, TürkiyeFırat University Hospital, Department of Dermatology, Elazığ, TürkiyeUniversal Eye Hospital, Clinic of Dermatology, Elazığ, TürkiyeObjective: This study aimed to investigate the potential relationship between the presence of Demodex mites and dermatological symptoms in patients with rosacea in the Central Anatolian Region of Türkiye. Methods: A total of 63 patients diagnosed with rosacea were enrolled in the study. Skin samples were obtained using a standardized skin surface biopsy technique, and a questionnaire was administered to assess skin symptoms. Statistical analysis was performed to evaluate the association between Demodex infestation and specific skin symptoms. Results: Among the study participants, 65.1% exhibited Demodex infestation. Statistical analysis revealed significant associations between the presence of Demodex and skin burning (p=0.018), skin pain (p=0.012), and skin stinging (p=0.001). However, no statistically significant associations were observed between Demodex presence and gender, skin dryness, itching, irritation, skin rash or the presence of red/pink bumps on the skin. Conclusion: This study provides evidence suggesting a potential role for Demodex mites in the pathogenesis of rosacea, specifically in relation to skin symptoms such as burning, pain, and stinging. The findings underscore the complexity of the relationship between Demodex infestation and rosacea and highlight the need for further research, including longitudinal and mechanistic studies, to better understand this association and its clinical implications. Ultimately, understanding the role of Demodex mites in rosacea may lead to innovative therapeutic approaches, offering hope for improved management of this challenging dermatological condition.https://www.turkiyeparazitolderg.org/articles/the-association-between-the-presence-of-human-facial-mites-lessemgreaterdemodex-lessemgreateracari-demodicidae-and-dermatological-symptoms-in-rosacea-patients-in-central-anatolia-turkiye/doi/tpd.galenos.2025.14632demodexrosaceadermatological symptoms |
| spellingShingle | Merve Kahraman Zübeyda Akın Polat Mustafa Esen Feride Çoban Gül The Association Between the Presence of Human Facial Mites Demodex (Acari, Demodicidae) and Dermatological Symptoms in Rosacea Patients in Central Anatolia, Türkiye Türkiye Parazitoloji Dergisi demodex rosacea dermatological symptoms |
| title | The Association Between the Presence of Human Facial Mites Demodex (Acari, Demodicidae) and Dermatological Symptoms in Rosacea Patients in Central Anatolia, Türkiye |
| title_full | The Association Between the Presence of Human Facial Mites Demodex (Acari, Demodicidae) and Dermatological Symptoms in Rosacea Patients in Central Anatolia, Türkiye |
| title_fullStr | The Association Between the Presence of Human Facial Mites Demodex (Acari, Demodicidae) and Dermatological Symptoms in Rosacea Patients in Central Anatolia, Türkiye |
| title_full_unstemmed | The Association Between the Presence of Human Facial Mites Demodex (Acari, Demodicidae) and Dermatological Symptoms in Rosacea Patients in Central Anatolia, Türkiye |
| title_short | The Association Between the Presence of Human Facial Mites Demodex (Acari, Demodicidae) and Dermatological Symptoms in Rosacea Patients in Central Anatolia, Türkiye |
| title_sort | association between the presence of human facial mites demodex acari demodicidae and dermatological symptoms in rosacea patients in central anatolia turkiye |
| topic | demodex rosacea dermatological symptoms |
| url | https://www.turkiyeparazitolderg.org/articles/the-association-between-the-presence-of-human-facial-mites-lessemgreaterdemodex-lessemgreateracari-demodicidae-and-dermatological-symptoms-in-rosacea-patients-in-central-anatolia-turkiye/doi/tpd.galenos.2025.14632 |
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