Strategies for in Silico Drug Discovery to Modulate Macromolecular Interactions Altered by Mutations
Most human diseases have genetic components, frequently single nucleotide variants (SNVs), which alter the wild type characteristics of macromolecules and their interactions. A straightforward approach for correcting such SNVs-related alterations is to seek small molecules, potential drugs, that can...
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| Main Authors: | Pitambar Poudel, Maria A. Miteva, Emil Alexov |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2025-04-01
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| Series: | Frontiers in Bioscience-Landmark |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/FBL/30/4/10.31083/FBL26339 |
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