Strategies for in Silico Drug Discovery to Modulate Macromolecular Interactions Altered by Mutations

Most human diseases have genetic components, frequently single nucleotide variants (SNVs), which alter the wild type characteristics of macromolecules and their interactions. A straightforward approach for correcting such SNVs-related alterations is to seek small molecules, potential drugs, that can...

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Bibliographic Details
Main Authors: Pitambar Poudel, Maria A. Miteva, Emil Alexov
Format: Article
Language:English
Published: IMR Press 2025-04-01
Series:Frontiers in Bioscience-Landmark
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Online Access:https://www.imrpress.com/journal/FBL/30/4/10.31083/FBL26339
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