Potential asthma biomarkers identified by nontargeted proteomics of extracellular vesicles in exhaled breath condensate

Potential asthma biomarkers identified by nontargeted proteomics of extracellular vesicles in exhaled breath condensate

Background: Bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD) are often misdiagnosed or undiagnosed, highlighting the need for more noninvasive and accessible diagnostic tools. Although exhaled breath condensate (EBC) is recognized as a biomarker resource for respiratory disease...

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Main Authors: Reina Hara, MD, Yoshito Takeda, MD, PhD, Takatoshi Enomoto, MD, Hanako Yoshimura, MD, PhD, Makoto Yamamoto, MD, Satoshi Tanizaki, MD, Yuya Shirai, MD, PhD, Takahiro Kawasaki, MD, PhD, Mana Nakayama, Saori Amiya, MD, Yuichi Adachi, MD, Yoshimi Noda, MD, Takayuki Niitsu, MD, Ryuya Edahiro, MD, PhD, Moto Yaga, MD, PhD, Yuki Hosono, MD, PhD, Maiko Naito, MD, PhD, Kentaro Masuhiro, MD, PhD, Yujiro Naito, MD, PhD, Takayuki Shiroyama, MD, PhD, Kotaro Miyake, MD, PhD, Kiyoharu Fukushima, MD, PhD, Shohei Koyama, MD, PhD, Kota Iwahori, MD, PhD, Haruhiko Hirata, MD, Izumi Nagatomo, MD, PhD, Yusuke Kawashima, PhD, Mari Nogami-Itoh, PhD, Atsushi Kumanogoh, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Exhaled breath condensate
proteomics
bioinformatics
biomarker
exosome
extracellular vesicles
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829325000335
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