Virus-induced Systemic Vasculitides: New Therapeutic Approaches

The best therapeutic strategy in virus-induced vasculitides should take into account the etiology of the disease and be adapted to the pathogenesis. The combination of antiviral treatments and plasma exchanges has been proven effective in polyarteritis nodosa (PAN...

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Main Author: Loïc Guillevin
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1080/17402520400001744
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author Loïc Guillevin
author_facet Loïc Guillevin
author_sort Loïc Guillevin
collection DOAJ
description The best therapeutic strategy in virus-induced vasculitides should take into account the etiology of the disease and be adapted to the pathogenesis. The combination of antiviral treatments and plasma exchanges has been proven effective in polyarteritis nodosa (PAN). In human immunodeficiency virus (HIV)-related vasculitis this strategy is also effective and does not jeopardize, like cytotoxic agents, the outcome of AIDS. In vasculitis related to HCV-associated cryoglobulinemia, plasma exchanges improve the outcome but the poor effectiveness of antiviral drugs is not able to favor, usually, a definite recovery of the patients and relapses are frequent.
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spelling doaj-art-3a47bef816b0420e854e7a97d1c213f32025-02-03T01:31:39ZengWileyClinical and Developmental Immunology1740-25221740-25302004-01-0111222723110.1080/17402520400001744Virus-induced Systemic Vasculitides: New Therapeutic ApproachesLoïc Guillevin0Department of Internal Medicine, Hôpital Cochin, AP-HP, Université René Descartes-Paris V, Paris, FranceThe best therapeutic strategy in virus-induced vasculitides should take into account the etiology of the disease and be adapted to the pathogenesis. The combination of antiviral treatments and plasma exchanges has been proven effective in polyarteritis nodosa (PAN). In human immunodeficiency virus (HIV)-related vasculitis this strategy is also effective and does not jeopardize, like cytotoxic agents, the outcome of AIDS. In vasculitis related to HCV-associated cryoglobulinemia, plasma exchanges improve the outcome but the poor effectiveness of antiviral drugs is not able to favor, usually, a definite recovery of the patients and relapses are frequent.http://dx.doi.org/10.1080/17402520400001744
spellingShingle Loïc Guillevin
Virus-induced Systemic Vasculitides: New Therapeutic Approaches
Clinical and Developmental Immunology
title Virus-induced Systemic Vasculitides: New Therapeutic Approaches
title_full Virus-induced Systemic Vasculitides: New Therapeutic Approaches
title_fullStr Virus-induced Systemic Vasculitides: New Therapeutic Approaches
title_full_unstemmed Virus-induced Systemic Vasculitides: New Therapeutic Approaches
title_short Virus-induced Systemic Vasculitides: New Therapeutic Approaches
title_sort virus induced systemic vasculitides new therapeutic approaches
url http://dx.doi.org/10.1080/17402520400001744
work_keys_str_mv AT loicguillevin virusinducedsystemicvasculitidesnewtherapeuticapproaches