Orlistat ameliorates lipid dysmetabolism in high-fat diet-induced mice via gut microbiota modulation

Orlistat ameliorates lipid dysmetabolism in high-fat diet-induced mice via gut microbiota modulation

Orlistat reduces obesity by inhibiting gastrointestinal lipases, thereby blocking the absorption and accumulation of triglycerides in the intestine. It has been shown to improve lipid metabolism and alter intestinal microbial communities in animals and humans. However, the impact of Orlistat-induced...

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Bibliographic Details
Main Authors: Chengyan Huang, Yuanhui He, Ping Chai, Zongxin Liu, Sirui Su, Yanhui Zhang, Yuelan Luo, Shuiping Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Microbiology
Subjects:
Orlistat
obesity
lipid metabolism
gut microbiota
microbiota transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1480500/full
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