A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons.

A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons.

<h4>Background</h4>Tissue inhibitor of metalloproteinases-1 (TIMP-1) displays pleiotropic activities, both dependent and independent of its inhibitory activity on matrix metalloproteinases (MMPs). In the central nervous system (CNS), TIMP-1 is strongly upregulated in reactive astrocytes...

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Main Authors: Adlane Ould-yahoui, Evelyne Tremblay, Oualid Sbai, Lotfi Ferhat, Anne Bernard, Eliane Charrat, Yatma Gueye, Ngee Han Lim, Keith Brew, Jean-Jacques Risso, Vincent Dive, Michel Khrestchatisky, Santiago Rivera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0008289&type=printable
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