Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control study

Introduction: Treatment of upper ureteric calculi has always remained a challenge for urologists. Treating the juxta-UPJ stones has been even more challenging. Difficulties in access, the possibility of up migration of stones, higher chances of leaving behind residual fragments, and the need for anc...

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Main Authors: T. P. Pradhyumna Koushik, Vivek Meyyappan, Nakul Baban Aher, Hariharasudhan Sekar, Gayathri Thiruvengadam, Sriram Krishnamoorthy
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Urology Annals
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Online Access:https://journals.lww.com/10.4103/ua.ua_48_24
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author T. P. Pradhyumna Koushik
Vivek Meyyappan
Nakul Baban Aher
Hariharasudhan Sekar
Gayathri Thiruvengadam
Sriram Krishnamoorthy
author_facet T. P. Pradhyumna Koushik
Vivek Meyyappan
Nakul Baban Aher
Hariharasudhan Sekar
Gayathri Thiruvengadam
Sriram Krishnamoorthy
author_sort T. P. Pradhyumna Koushik
collection DOAJ
description Introduction: Treatment of upper ureteric calculi has always remained a challenge for urologists. Treating the juxta-UPJ stones has been even more challenging. Difficulties in access, the possibility of up migration of stones, higher chances of leaving behind residual fragments, and the need for ancillary procedures like ESWL or relook URS have been a few inherent limitations in treating such stones. Offering PCNL for smaller stones was considered an overkill by many urologists. However, with the advent of miniaturized PCNL and improvisations in RIRS techniques, more and more of such stones are tackled with ease. Objective: To compare the safety and efficacy of mini-percutaneous nephrolithotomy (Miniperc PCNL) and retrograde intrarenal surgery (RIRS) in the management of juxta pelvi-ureteric junction (PUJ) calculi, located between 1 and 2 cm from PUJ. Materials and Methods: A prospective, randomized study was done on 100 patients with upper ureteric stones up to 2 cm in size and within 2 cm from PUJ. Patients with odd numbers were assigned Group A (Miniperc PCNL, n = 50) and even numbers were assigned to Group B (RIRS, n = 50). Results: Stone-free rates were 92% for Group A and 72% for Group B (P < 0.0174). Mean operative time was significantly shorter in Group A than Group B (53.2 min vs. 68.52 min, P < 0.001). Hospital stay was longer for Group A (47.42 h) compared to Group B (29.36 h, P < 0.001). Lasing time was more with RIRS than with PCNL (10.18 min vs. 3.24 min, P < 0.001). The complications were more in Group A than Group B, but not significant (P = 0.160). Postoperative pain and time to return to normal activities were significantly better in Group B RIRS (P < 0.001). Conclusions: Both Miniperc PCNL and RIRS are the effective treatments for upper ureteric stones. Miniperc PCNL has advantages in terms of shorter operative time, lesser lasing time, and better stone free rates. RIRS demonstrated reduced hospital stay, reduced postoperative pain, and quicker recovery. Miniperc PCNL showed a higher stone-free rate for treating upper ureteric stones up to 2 cm. RIRS is effective for treating stones up to 2 cm in upper ureter reducing the complications associated with Miniperc PCNL.
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spelling doaj-art-3a2b622baf4b4ce7845a2ebd9c0024732025-02-06T07:30:03ZengWolters Kluwer Medknow PublicationsUrology Annals0974-77960974-78342025-01-0117191610.4103/ua.ua_48_24Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control studyT. P. Pradhyumna KoushikVivek MeyyappanNakul Baban AherHariharasudhan SekarGayathri ThiruvengadamSriram KrishnamoorthyIntroduction: Treatment of upper ureteric calculi has always remained a challenge for urologists. Treating the juxta-UPJ stones has been even more challenging. Difficulties in access, the possibility of up migration of stones, higher chances of leaving behind residual fragments, and the need for ancillary procedures like ESWL or relook URS have been a few inherent limitations in treating such stones. Offering PCNL for smaller stones was considered an overkill by many urologists. However, with the advent of miniaturized PCNL and improvisations in RIRS techniques, more and more of such stones are tackled with ease. Objective: To compare the safety and efficacy of mini-percutaneous nephrolithotomy (Miniperc PCNL) and retrograde intrarenal surgery (RIRS) in the management of juxta pelvi-ureteric junction (PUJ) calculi, located between 1 and 2 cm from PUJ. Materials and Methods: A prospective, randomized study was done on 100 patients with upper ureteric stones up to 2 cm in size and within 2 cm from PUJ. Patients with odd numbers were assigned Group A (Miniperc PCNL, n = 50) and even numbers were assigned to Group B (RIRS, n = 50). Results: Stone-free rates were 92% for Group A and 72% for Group B (P < 0.0174). Mean operative time was significantly shorter in Group A than Group B (53.2 min vs. 68.52 min, P < 0.001). Hospital stay was longer for Group A (47.42 h) compared to Group B (29.36 h, P < 0.001). Lasing time was more with RIRS than with PCNL (10.18 min vs. 3.24 min, P < 0.001). The complications were more in Group A than Group B, but not significant (P = 0.160). Postoperative pain and time to return to normal activities were significantly better in Group B RIRS (P < 0.001). Conclusions: Both Miniperc PCNL and RIRS are the effective treatments for upper ureteric stones. Miniperc PCNL has advantages in terms of shorter operative time, lesser lasing time, and better stone free rates. RIRS demonstrated reduced hospital stay, reduced postoperative pain, and quicker recovery. Miniperc PCNL showed a higher stone-free rate for treating upper ureteric stones up to 2 cm. RIRS is effective for treating stones up to 2 cm in upper ureter reducing the complications associated with Miniperc PCNL.https://journals.lww.com/10.4103/ua.ua_48_24laserpercutaneous nephrolithotomyretrograde intrarenal surgery
spellingShingle T. P. Pradhyumna Koushik
Vivek Meyyappan
Nakul Baban Aher
Hariharasudhan Sekar
Gayathri Thiruvengadam
Sriram Krishnamoorthy
Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control study
Urology Annals
laser
percutaneous nephrolithotomy
retrograde intrarenal surgery
title Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control study
title_full Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control study
title_fullStr Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control study
title_full_unstemmed Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control study
title_short Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control study
title_sort miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero pelvic junction upper ureteric calculi a prospective randomized control study
topic laser
percutaneous nephrolithotomy
retrograde intrarenal surgery
url https://journals.lww.com/10.4103/ua.ua_48_24
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