Antibody-Mediated Rejection in Kidney Transplantation: A Review
Antibody mediated rejection (AMR) poses a significant and continued challenge for long term graft survival in kidney transplantation. However, in the recent years, there has emerged an increased understanding of the varied manifestations of the antibody mediated processes in kidney transplantation....
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Journal of Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2012/193724 |
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| Summary: | Antibody mediated rejection (AMR) poses a significant and continued challenge for long term
graft survival in kidney transplantation. However, in the recent years, there has emerged an
increased understanding of the varied manifestations of the antibody mediated processes in
kidney transplantation. In this article, we briefly discuss the various histopathological and clinical
manifestations of AMRs, along with describing the techniques and methods which have made it
easier to define and diagnose these rejections. We also review the emerging issues of C4d
negative AMR, its significance in long term allograft survival and provide a brief summary of the
current management strategies for managing AMRs in kidney transplantation. |
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| ISSN: | 2090-0007 2090-0015 |