Categorization of 34 computational methods to detect spatially variable genes from spatially resolved transcriptomics data
Abstract In the analysis of spatially resolved transcriptomics data, detecting spatially variable genes (SVGs) is crucial. Numerous computational methods exist, but varying SVG definitions and methodologies lead to incomparable results. We review 34 state-of-the-art methods, classifying SVGs into th...
Saved in:
Main Authors: | Guanao Yan, Shuo Harper Hua, Jingyi Jessica Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-025-56080-w |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Spatially resolved transcriptomics reveals gene expression characteristics in uveal melanoma
by: Jing-Ying Xiu, et al.
Published: (2025-01-01) -
Protocol to denoise spatially resolved transcriptomics data utilizing optimal transport-based gene filtering algorithm
by: Lin Du, et al.
Published: (2025-03-01) -
Statistical identification of cell type-specific spatially variable genes in spatial transcriptomics
by: Lulu Shang, et al.
Published: (2025-01-01) -
Statistical and computational methods for enabling the clinical and translational application of spatial transcriptomics
by: Peijun Wu, et al.
Published: (2024-12-01) -
Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning
by: Zhuohan Yu, et al.
Published: (2025-01-01)