Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen

While splenic complications like hypersplenism, sequestration crisis, and infarction are commonly reported in sickle cell variants like sickle cell beta-plus thalassemia, splenic rupture with hematoma is rare. We present a case of a 32-year-old young male who presented with dull left upper quadrant...

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Main Authors: Suyash Dahal, Sumit Dahal, Dipesh K. C. Ghimire, Ebad Ur Rahman, Eliza Sharma
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2017/3819457
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author Suyash Dahal
Sumit Dahal
Dipesh K. C. Ghimire
Ebad Ur Rahman
Eliza Sharma
author_facet Suyash Dahal
Sumit Dahal
Dipesh K. C. Ghimire
Ebad Ur Rahman
Eliza Sharma
author_sort Suyash Dahal
collection DOAJ
description While splenic complications like hypersplenism, sequestration crisis, and infarction are commonly reported in sickle cell variants like sickle cell beta-plus thalassemia, splenic rupture with hematoma is rare. We present a case of a 32-year-old young male who presented with dull left upper quadrant pain who was found to have multiple subcapsular splenic lacerations and hematoma on abdominal imaging. Hemoglobin electrophoresis confirmed sickle cell beta-plus thalassemia in the patient. There was no history of trauma, and rest of the workup for possible cause of spontaneous rupture of spleen was negative. With the patient refusing splenectomy, he was managed conservatively. Clinicians need to be aware of this rare complication of sickle cell variants.
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institution Kabale University
issn 2090-6560
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publishDate 2017-01-01
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series Case Reports in Hematology
spelling doaj-art-3a127709ce124d9fa8ca4337eb29c5742025-02-03T01:21:35ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/38194573819457Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the SpleenSuyash Dahal0Sumit Dahal1Dipesh K. C. Ghimire2Ebad Ur Rahman3Eliza Sharma4KIST Medical College and Teaching Hospital, Lalitpur, NepalInterfaith Medical Center, Brooklyn, NY, USAInterfaith Medical Center, Brooklyn, NY, USAInterfaith Medical Center, Brooklyn, NY, USAMaimonides Medical Center, Brooklyn, NY, USAWhile splenic complications like hypersplenism, sequestration crisis, and infarction are commonly reported in sickle cell variants like sickle cell beta-plus thalassemia, splenic rupture with hematoma is rare. We present a case of a 32-year-old young male who presented with dull left upper quadrant pain who was found to have multiple subcapsular splenic lacerations and hematoma on abdominal imaging. Hemoglobin electrophoresis confirmed sickle cell beta-plus thalassemia in the patient. There was no history of trauma, and rest of the workup for possible cause of spontaneous rupture of spleen was negative. With the patient refusing splenectomy, he was managed conservatively. Clinicians need to be aware of this rare complication of sickle cell variants.http://dx.doi.org/10.1155/2017/3819457
spellingShingle Suyash Dahal
Sumit Dahal
Dipesh K. C. Ghimire
Ebad Ur Rahman
Eliza Sharma
Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen
Case Reports in Hematology
title Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen
title_full Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen
title_fullStr Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen
title_full_unstemmed Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen
title_short Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen
title_sort sickle cell beta plus thalassemia with subcapsular hematoma of the spleen
url http://dx.doi.org/10.1155/2017/3819457
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