A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: Leukocytopenia

Polyacrylamide hydrogel (PAAG) has been used as an injectable filler for soft tissue augmentation of different body parts, such as the face, breasts, and penis. However, this is the first report of leukocytopenia after injection of a large amount of PAAG in the epicranial aponeurosis. After receivin...

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Main Authors: Li Rong, Shi-Jie Lan, Ying Shao, Zhe Chen, Duo Zhang
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2015/695359
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author Li Rong
Shi-Jie Lan
Ying Shao
Zhe Chen
Duo Zhang
author_facet Li Rong
Shi-Jie Lan
Ying Shao
Zhe Chen
Duo Zhang
author_sort Li Rong
collection DOAJ
description Polyacrylamide hydrogel (PAAG) has been used as an injectable filler for soft tissue augmentation of different body parts, such as the face, breasts, and penis. However, this is the first report of leukocytopenia after injection of a large amount of PAAG in the epicranial aponeurosis. After receiving PAAG injection for craniofacial contouring, the female patient described herein experienced recurrent swelling, temporal pain (particularly with changes in ambient temperature and facial expression), and ultimately leukocytopenia due to widespread migration of the injected PAAG. We removed most of the PAAG from the affected tissues and the leukocytopenia disappeared 1 year after the operation. Based on this case, we hypothesize that injection of a large amount of PAAG into tissues that have ample blood supply, such as the epicranial aponeurosis, may induce leukocytopenia.
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issn 1687-9627
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language English
publishDate 2015-01-01
publisher Wiley
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series Case Reports in Medicine
spelling doaj-art-3a0d3185f39b43adb58e708e80c799302025-02-03T01:23:46ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/695359695359A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: LeukocytopeniaLi Rong0Shi-Jie Lan1Ying Shao2Zhe Chen3Duo Zhang4Department of Plastic and Aesthetic Surgery, First Hospital of Jilin University, Chaoyang District, Changchun, Jilin 130021, ChinaDepartment of Hematology and Oncology, First Hospital of Jilin University, Chaoyang District, Changchun, Jilin 130021, ChinaDepartment of Plastic and Aesthetic Surgery, First Hospital of Jilin University, Chaoyang District, Changchun, Jilin 130021, ChinaDepartment of Plastic and Aesthetic Surgery, First Hospital of Jilin University, Chaoyang District, Changchun, Jilin 130021, ChinaDepartment of Plastic and Aesthetic Surgery, First Hospital of Jilin University, Chaoyang District, Changchun, Jilin 130021, ChinaPolyacrylamide hydrogel (PAAG) has been used as an injectable filler for soft tissue augmentation of different body parts, such as the face, breasts, and penis. However, this is the first report of leukocytopenia after injection of a large amount of PAAG in the epicranial aponeurosis. After receiving PAAG injection for craniofacial contouring, the female patient described herein experienced recurrent swelling, temporal pain (particularly with changes in ambient temperature and facial expression), and ultimately leukocytopenia due to widespread migration of the injected PAAG. We removed most of the PAAG from the affected tissues and the leukocytopenia disappeared 1 year after the operation. Based on this case, we hypothesize that injection of a large amount of PAAG into tissues that have ample blood supply, such as the epicranial aponeurosis, may induce leukocytopenia.http://dx.doi.org/10.1155/2015/695359
spellingShingle Li Rong
Shi-Jie Lan
Ying Shao
Zhe Chen
Duo Zhang
A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: Leukocytopenia
Case Reports in Medicine
title A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: Leukocytopenia
title_full A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: Leukocytopenia
title_fullStr A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: Leukocytopenia
title_full_unstemmed A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: Leukocytopenia
title_short A Case of Special Complication following a Large Amount of Polyacrylamide Hydrogel Injected into the Epicranial Aponeurosis: Leukocytopenia
title_sort case of special complication following a large amount of polyacrylamide hydrogel injected into the epicranial aponeurosis leukocytopenia
url http://dx.doi.org/10.1155/2015/695359
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