Hepatitis B Associated Monoclonal Gammopathy That Resolved after Successful Liver Transplant

Monoclonal gammopathy of undetermined significance (MGUS) has been most commonly associated with diseases like multiple myeloma, Waldenstrom's macroglobulinemia, primary systemic amyloidosis, HIV, and other lymphoproliferative disorders. There has been an isolated report of MGUS in patients coi...

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Main Authors: P. Sreenivasan, S. Nair
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2009/103784
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author P. Sreenivasan
S. Nair
author_facet P. Sreenivasan
S. Nair
author_sort P. Sreenivasan
collection DOAJ
description Monoclonal gammopathy of undetermined significance (MGUS) has been most commonly associated with diseases like multiple myeloma, Waldenstrom's macroglobulinemia, primary systemic amyloidosis, HIV, and other lymphoproliferative disorders. There has been an isolated report of MGUS in patients coinfected with HIV and Hepatitis B, as the work by Amara et al. in 2006. Here, we report a case of IgA-kappa light chain gammopathy secondary to Hepatitis B infection, which resolved after liver transplantation. To our knowledge, this is the first reported case of M protein spike seen in the context of Hepatitis B infection only.
format Article
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institution Kabale University
issn 2090-0007
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publishDate 2009-01-01
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series Journal of Transplantation
spelling doaj-art-39db32a2afe04796947d8f8756d500a02025-02-03T01:07:13ZengWileyJournal of Transplantation2090-00072090-00152009-01-01200910.1155/2009/103784103784Hepatitis B Associated Monoclonal Gammopathy That Resolved after Successful Liver TransplantP. Sreenivasan0S. Nair1Section of Hepatology, Division of Gastroenterology, Department of Medicine, Methodist University Hospital, University of Tennessee Health Science Center, Memphis, TN 38163, USASection of Hepatology, Division of Gastroenterology, Department of Medicine, Methodist University Hospital, University of Tennessee Health Science Center, Memphis, TN 38163, USAMonoclonal gammopathy of undetermined significance (MGUS) has been most commonly associated with diseases like multiple myeloma, Waldenstrom's macroglobulinemia, primary systemic amyloidosis, HIV, and other lymphoproliferative disorders. There has been an isolated report of MGUS in patients coinfected with HIV and Hepatitis B, as the work by Amara et al. in 2006. Here, we report a case of IgA-kappa light chain gammopathy secondary to Hepatitis B infection, which resolved after liver transplantation. To our knowledge, this is the first reported case of M protein spike seen in the context of Hepatitis B infection only.http://dx.doi.org/10.1155/2009/103784
spellingShingle P. Sreenivasan
S. Nair
Hepatitis B Associated Monoclonal Gammopathy That Resolved after Successful Liver Transplant
Journal of Transplantation
title Hepatitis B Associated Monoclonal Gammopathy That Resolved after Successful Liver Transplant
title_full Hepatitis B Associated Monoclonal Gammopathy That Resolved after Successful Liver Transplant
title_fullStr Hepatitis B Associated Monoclonal Gammopathy That Resolved after Successful Liver Transplant
title_full_unstemmed Hepatitis B Associated Monoclonal Gammopathy That Resolved after Successful Liver Transplant
title_short Hepatitis B Associated Monoclonal Gammopathy That Resolved after Successful Liver Transplant
title_sort hepatitis b associated monoclonal gammopathy that resolved after successful liver transplant
url http://dx.doi.org/10.1155/2009/103784
work_keys_str_mv AT psreenivasan hepatitisbassociatedmonoclonalgammopathythatresolvedaftersuccessfullivertransplant
AT snair hepatitisbassociatedmonoclonalgammopathythatresolvedaftersuccessfullivertransplant