T helper cell polarisation as a measure of the maturation of the immune response
Background: T helper cell polarisation is important under chronic immune stimulatory conditions and drives the type of the evolving immune response. Mice treated with superantigens in vivo display strong effects on Th subset differentiation. The aim of the study was to detect the intrinsic capacity...
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Format: | Article |
Language: | English |
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Wiley
2003-01-01
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Series: | Mediators of Inflammation |
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Online Access: | http://dx.doi.org/10.1080/0929350310001619744 |
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author | Scott B. Cameron Ellen H. Stolte Anthony W. Chow Huub F. J. Savelkoul |
author_facet | Scott B. Cameron Ellen H. Stolte Anthony W. Chow Huub F. J. Savelkoul |
author_sort | Scott B. Cameron |
collection | DOAJ |
description | Background: T helper cell polarisation is important under chronic immune stimulatory conditions and drives the type of the evolving immune response. Mice treated with superantigens in vivo display strong effects on Th subset differentiation. The aim of the study was to detect the intrinsic capacity of T cells to polarise under various ex vivo conditions. |
format | Article |
id | doaj-art-39d2582e73c4404699f9d97e85287263 |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 2003-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-39d2582e73c4404699f9d97e852872632025-02-03T05:59:23ZengWileyMediators of Inflammation0962-93511466-18612003-01-0112528529210.1080/0929350310001619744T helper cell polarisation as a measure of the maturation of the immune responseScott B. Cameron0Ellen H. Stolte1Anthony W. Chow2Huub F. J. Savelkoul3Division of Infectious Diseases, University of British Columbia, Vancouver, CanadaCell Biology and Immunology Group, Wageningen University, P.O. Box 338, Wageningen, 6700AH, The NetherlandsDivision of Infectious Diseases, University of British Columbia, Vancouver, CanadaCell Biology and Immunology Group, Wageningen University, P.O. Box 338, Wageningen, 6700AH, The NetherlandsBackground: T helper cell polarisation is important under chronic immune stimulatory conditions and drives the type of the evolving immune response. Mice treated with superantigens in vivo display strong effects on Th subset differentiation. The aim of the study was to detect the intrinsic capacity of T cells to polarise under various ex vivo conditions.http://dx.doi.org/10.1080/0929350310001619744Th cellcytokinesPolarisationMagnetic-activated cell sortingIntracellular cytokine stainingFluorescent-activated cell sorter. |
spellingShingle | Scott B. Cameron Ellen H. Stolte Anthony W. Chow Huub F. J. Savelkoul T helper cell polarisation as a measure of the maturation of the immune response Mediators of Inflammation Th cell cytokines Polarisation Magnetic-activated cell sorting Intracellular cytokine staining Fluorescent-activated cell sorter. |
title | T helper cell polarisation as a measure of the maturation of the immune response |
title_full | T helper cell polarisation as a measure of the maturation of the immune response |
title_fullStr | T helper cell polarisation as a measure of the maturation of the immune response |
title_full_unstemmed | T helper cell polarisation as a measure of the maturation of the immune response |
title_short | T helper cell polarisation as a measure of the maturation of the immune response |
title_sort | t helper cell polarisation as a measure of the maturation of the immune response |
topic | Th cell cytokines Polarisation Magnetic-activated cell sorting Intracellular cytokine staining Fluorescent-activated cell sorter. |
url | http://dx.doi.org/10.1080/0929350310001619744 |
work_keys_str_mv | AT scottbcameron thelpercellpolarisationasameasureofthematurationoftheimmuneresponse AT ellenhstolte thelpercellpolarisationasameasureofthematurationoftheimmuneresponse AT anthonywchow thelpercellpolarisationasameasureofthematurationoftheimmuneresponse AT huubfjsavelkoul thelpercellpolarisationasameasureofthematurationoftheimmuneresponse |