T helper cell polarisation as a measure of the maturation of the immune response

Background: T helper cell polarisation is important under chronic immune stimulatory conditions and drives the type of the evolving immune response. Mice treated with superantigens in vivo display strong effects on Th subset differentiation. The aim of the study was to detect the intrinsic capacity...

Full description

Saved in:
Bibliographic Details
Main Authors: Scott B. Cameron, Ellen H. Stolte, Anthony W. Chow, Huub F. J. Savelkoul
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Mediators of Inflammation
Subjects:
Online Access:http://dx.doi.org/10.1080/0929350310001619744
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832552153214877696
author Scott B. Cameron
Ellen H. Stolte
Anthony W. Chow
Huub F. J. Savelkoul
author_facet Scott B. Cameron
Ellen H. Stolte
Anthony W. Chow
Huub F. J. Savelkoul
author_sort Scott B. Cameron
collection DOAJ
description Background: T helper cell polarisation is important under chronic immune stimulatory conditions and drives the type of the evolving immune response. Mice treated with superantigens in vivo display strong effects on Th subset differentiation. The aim of the study was to detect the intrinsic capacity of T cells to polarise under various ex vivo conditions.
format Article
id doaj-art-39d2582e73c4404699f9d97e85287263
institution Kabale University
issn 0962-9351
1466-1861
language English
publishDate 2003-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-39d2582e73c4404699f9d97e852872632025-02-03T05:59:23ZengWileyMediators of Inflammation0962-93511466-18612003-01-0112528529210.1080/0929350310001619744T helper cell polarisation as a measure of the maturation of the immune responseScott B. Cameron0Ellen H. Stolte1Anthony W. Chow2Huub F. J. Savelkoul3Division of Infectious Diseases, University of British Columbia, Vancouver, CanadaCell Biology and Immunology Group, Wageningen University, P.O. Box 338, Wageningen, 6700AH, The NetherlandsDivision of Infectious Diseases, University of British Columbia, Vancouver, CanadaCell Biology and Immunology Group, Wageningen University, P.O. Box 338, Wageningen, 6700AH, The NetherlandsBackground: T helper cell polarisation is important under chronic immune stimulatory conditions and drives the type of the evolving immune response. Mice treated with superantigens in vivo display strong effects on Th subset differentiation. The aim of the study was to detect the intrinsic capacity of T cells to polarise under various ex vivo conditions.http://dx.doi.org/10.1080/0929350310001619744Th cellcytokinesPolarisationMagnetic-activated cell sortingIntracellular cytokine stainingFluorescent-activated cell sorter.
spellingShingle Scott B. Cameron
Ellen H. Stolte
Anthony W. Chow
Huub F. J. Savelkoul
T helper cell polarisation as a measure of the maturation of the immune response
Mediators of Inflammation
Th cell
cytokines
Polarisation
Magnetic-activated cell sorting
Intracellular cytokine staining
Fluorescent-activated cell sorter.
title T helper cell polarisation as a measure of the maturation of the immune response
title_full T helper cell polarisation as a measure of the maturation of the immune response
title_fullStr T helper cell polarisation as a measure of the maturation of the immune response
title_full_unstemmed T helper cell polarisation as a measure of the maturation of the immune response
title_short T helper cell polarisation as a measure of the maturation of the immune response
title_sort t helper cell polarisation as a measure of the maturation of the immune response
topic Th cell
cytokines
Polarisation
Magnetic-activated cell sorting
Intracellular cytokine staining
Fluorescent-activated cell sorter.
url http://dx.doi.org/10.1080/0929350310001619744
work_keys_str_mv AT scottbcameron thelpercellpolarisationasameasureofthematurationoftheimmuneresponse
AT ellenhstolte thelpercellpolarisationasameasureofthematurationoftheimmuneresponse
AT anthonywchow thelpercellpolarisationasameasureofthematurationoftheimmuneresponse
AT huubfjsavelkoul thelpercellpolarisationasameasureofthematurationoftheimmuneresponse