Comparison of routine blood parameters by altitude and residence duration in the Western Sichuan Plateau
Background: This study explores how routine blood test parameters change over time in acclimatized individuals at different altitudes on the Western Sichuan Plateau. Methods: Healthy men aged 20–40 from low-altitude areas who moved to Ganzi Prefecture to live and work were recruited. The observation...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Practical Laboratory Medicine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352551725000204 |
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| author | Liang Wan Qing Yuan Mingxia Tang Zhu Zhu Yanwu Liu Zhenglin Huang Shuzhi Zhou Ling Zhang Qiaoling Wang Yuntao Guo Jian Yang |
| author_facet | Liang Wan Qing Yuan Mingxia Tang Zhu Zhu Yanwu Liu Zhenglin Huang Shuzhi Zhou Ling Zhang Qiaoling Wang Yuntao Guo Jian Yang |
| author_sort | Liang Wan |
| collection | DOAJ |
| description | Background: This study explores how routine blood test parameters change over time in acclimatized individuals at different altitudes on the Western Sichuan Plateau. Methods: Healthy men aged 20–40 from low-altitude areas who moved to Ganzi Prefecture to live and work were recruited. The observation sites were Guzan Town (1400 m), Kangding County Seat (2500 m), Luhuo County Seat (3400 m), and Litang County Seat (4100 m). Participants at the same altitude were grouped according to residence duration. The relationships between blood test parameters, altitude, and residence duration were analyzed. Results: After moving to the plateau, white blood cell, red blood cell, hemoglobin, and hematocrit levels rose quickly in the short term, then declined and stabilized. In contrast, platelet levels increased steadily and were positively correlated with altitude. Conclusions: Changes in blood parameters during high-altitude acclimatization are significant physiological responses to hypoxia and are affected by both altitude and residence duration. |
| format | Article |
| id | doaj-art-39cecb50b1374f48a9b9631f1eb8ac6f |
| institution | OA Journals |
| issn | 2352-5517 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Practical Laboratory Medicine |
| spelling | doaj-art-39cecb50b1374f48a9b9631f1eb8ac6f2025-08-20T02:09:11ZengElsevierPractical Laboratory Medicine2352-55172025-07-0145e0046710.1016/j.plabm.2025.e00467Comparison of routine blood parameters by altitude and residence duration in the Western Sichuan PlateauLiang Wan0Qing Yuan1Mingxia Tang2Zhu Zhu3Yanwu Liu4Zhenglin Huang5Shuzhi Zhou6Ling Zhang7Qiaoling Wang8Yuntao Guo9Jian Yang10Yaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaYaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaCorresponding author.; Yaan People's Hospital, No. 8 Ankang Road, Yucheng District, Ya'an City, 625000, ChinaBackground: This study explores how routine blood test parameters change over time in acclimatized individuals at different altitudes on the Western Sichuan Plateau. Methods: Healthy men aged 20–40 from low-altitude areas who moved to Ganzi Prefecture to live and work were recruited. The observation sites were Guzan Town (1400 m), Kangding County Seat (2500 m), Luhuo County Seat (3400 m), and Litang County Seat (4100 m). Participants at the same altitude were grouped according to residence duration. The relationships between blood test parameters, altitude, and residence duration were analyzed. Results: After moving to the plateau, white blood cell, red blood cell, hemoglobin, and hematocrit levels rose quickly in the short term, then declined and stabilized. In contrast, platelet levels increased steadily and were positively correlated with altitude. Conclusions: Changes in blood parameters during high-altitude acclimatization are significant physiological responses to hypoxia and are affected by both altitude and residence duration.http://www.sciencedirect.com/science/article/pii/S2352551725000204High-altitude acclimatizationRoutine blood testAltitudeResidence durationHypoxia |
| spellingShingle | Liang Wan Qing Yuan Mingxia Tang Zhu Zhu Yanwu Liu Zhenglin Huang Shuzhi Zhou Ling Zhang Qiaoling Wang Yuntao Guo Jian Yang Comparison of routine blood parameters by altitude and residence duration in the Western Sichuan Plateau Practical Laboratory Medicine High-altitude acclimatization Routine blood test Altitude Residence duration Hypoxia |
| title | Comparison of routine blood parameters by altitude and residence duration in the Western Sichuan Plateau |
| title_full | Comparison of routine blood parameters by altitude and residence duration in the Western Sichuan Plateau |
| title_fullStr | Comparison of routine blood parameters by altitude and residence duration in the Western Sichuan Plateau |
| title_full_unstemmed | Comparison of routine blood parameters by altitude and residence duration in the Western Sichuan Plateau |
| title_short | Comparison of routine blood parameters by altitude and residence duration in the Western Sichuan Plateau |
| title_sort | comparison of routine blood parameters by altitude and residence duration in the western sichuan plateau |
| topic | High-altitude acclimatization Routine blood test Altitude Residence duration Hypoxia |
| url | http://www.sciencedirect.com/science/article/pii/S2352551725000204 |
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