The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss

The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a...

Full description

Saved in:
Bibliographic Details
Main Authors: Aruchuna Ruban, Hutan Ashrafian, Julian P. Teare
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2018/7823182
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832564742356467712
author Aruchuna Ruban
Hutan Ashrafian
Julian P. Teare
author_facet Aruchuna Ruban
Hutan Ashrafian
Julian P. Teare
author_sort Aruchuna Ruban
collection DOAJ
description The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice.
format Article
id doaj-art-39bfe95b6a78459da487d12b25ae4783
institution Kabale University
issn 1687-6121
1687-630X
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Gastroenterology Research and Practice
spelling doaj-art-39bfe95b6a78459da487d12b25ae47832025-02-03T01:10:18ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/78231827823182The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight LossAruchuna Ruban0Hutan Ashrafian1Julian P. Teare2Department of Surgery and Cancer, Imperial College, London, UKDepartment of Surgery and Cancer, Imperial College, London, UKDepartment of Surgery and Cancer, Imperial College, London, UKThe rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice.http://dx.doi.org/10.1155/2018/7823182
spellingShingle Aruchuna Ruban
Hutan Ashrafian
Julian P. Teare
The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
Gastroenterology Research and Practice
title The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_full The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_fullStr The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_full_unstemmed The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_short The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
title_sort endobarrier duodenal jejunal bypass liner for diabetes and weight loss
url http://dx.doi.org/10.1155/2018/7823182
work_keys_str_mv AT aruchunaruban theendobarrierduodenaljejunalbypasslinerfordiabetesandweightloss
AT hutanashrafian theendobarrierduodenaljejunalbypasslinerfordiabetesandweightloss
AT julianpteare theendobarrierduodenaljejunalbypasslinerfordiabetesandweightloss
AT aruchunaruban endobarrierduodenaljejunalbypasslinerfordiabetesandweightloss
AT hutanashrafian endobarrierduodenaljejunalbypasslinerfordiabetesandweightloss
AT julianpteare endobarrierduodenaljejunalbypasslinerfordiabetesandweightloss