The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss
The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a...
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Format: | Article |
Language: | English |
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Wiley
2018-01-01
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Series: | Gastroenterology Research and Practice |
Online Access: | http://dx.doi.org/10.1155/2018/7823182 |
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author | Aruchuna Ruban Hutan Ashrafian Julian P. Teare |
author_facet | Aruchuna Ruban Hutan Ashrafian Julian P. Teare |
author_sort | Aruchuna Ruban |
collection | DOAJ |
description | The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice. |
format | Article |
id | doaj-art-39bfe95b6a78459da487d12b25ae4783 |
institution | Kabale University |
issn | 1687-6121 1687-630X |
language | English |
publishDate | 2018-01-01 |
publisher | Wiley |
record_format | Article |
series | Gastroenterology Research and Practice |
spelling | doaj-art-39bfe95b6a78459da487d12b25ae47832025-02-03T01:10:18ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/78231827823182The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight LossAruchuna Ruban0Hutan Ashrafian1Julian P. Teare2Department of Surgery and Cancer, Imperial College, London, UKDepartment of Surgery and Cancer, Imperial College, London, UKDepartment of Surgery and Cancer, Imperial College, London, UKThe rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice.http://dx.doi.org/10.1155/2018/7823182 |
spellingShingle | Aruchuna Ruban Hutan Ashrafian Julian P. Teare The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss Gastroenterology Research and Practice |
title | The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss |
title_full | The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss |
title_fullStr | The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss |
title_full_unstemmed | The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss |
title_short | The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss |
title_sort | endobarrier duodenal jejunal bypass liner for diabetes and weight loss |
url | http://dx.doi.org/10.1155/2018/7823182 |
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