Myoepithelial Carcinoma of the Breast Treated with Surgery and Chemotherapy

Myoepithelial carcinoma (malignant myoepithelioma) of the breast is a rare tumor, for which only a limited number of reports have been published. Most of the reports emphasized diagnosis and pathology but not biological behavior and treatment. We report a 61-year-old patient with breast myoepithelia...

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Main Authors: Yumi Endo, Hiroshi Sugiura, Hiroko Yamashita, Satoru Takahashi, Nobuyasu Yoshimoto, Mai Iwasa, Tomoko Asano, Tatsuya Toyama
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2013/164761
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author Yumi Endo
Hiroshi Sugiura
Hiroko Yamashita
Satoru Takahashi
Nobuyasu Yoshimoto
Mai Iwasa
Tomoko Asano
Tatsuya Toyama
author_facet Yumi Endo
Hiroshi Sugiura
Hiroko Yamashita
Satoru Takahashi
Nobuyasu Yoshimoto
Mai Iwasa
Tomoko Asano
Tatsuya Toyama
author_sort Yumi Endo
collection DOAJ
description Myoepithelial carcinoma (malignant myoepithelioma) of the breast is a rare tumor, for which only a limited number of reports have been published. Most of the reports emphasized diagnosis and pathology but not biological behavior and treatment. We report a 61-year-old patient with breast myoepithelial carcinoma who developed locoregional and distant metastases and received many chemotherapy regimens. She presented with an elastic hard mass of the left breast. Breast conserving surgery was performed as part of both diagnosis and treatment. From the results of histological and immunohistochemical examinations, this case was considered to be a myoepithelial carcinoma. Fifteen months after the completion of adjuvant radiotherapy, distant metastasis of the left parasternal lymph node metastasis developed. She was treated by further excision and received a total of four regimens of chemotherapy including a combination of doxorubicin and cyclophosphamide. She received chemotherapy for 20 months after the diagnosis of metastasis.
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institution Kabale University
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language English
publishDate 2013-01-01
publisher Wiley
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series Case Reports in Oncological Medicine
spelling doaj-art-39939fbd6d974d54a4df37b552f39c532025-02-03T07:24:34ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/164761164761Myoepithelial Carcinoma of the Breast Treated with Surgery and ChemotherapyYumi Endo0Hiroshi Sugiura1Hiroko Yamashita2Satoru Takahashi3Nobuyasu Yoshimoto4Mai Iwasa5Tomoko Asano6Tatsuya Toyama7Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, JapanMyoepithelial carcinoma (malignant myoepithelioma) of the breast is a rare tumor, for which only a limited number of reports have been published. Most of the reports emphasized diagnosis and pathology but not biological behavior and treatment. We report a 61-year-old patient with breast myoepithelial carcinoma who developed locoregional and distant metastases and received many chemotherapy regimens. She presented with an elastic hard mass of the left breast. Breast conserving surgery was performed as part of both diagnosis and treatment. From the results of histological and immunohistochemical examinations, this case was considered to be a myoepithelial carcinoma. Fifteen months after the completion of adjuvant radiotherapy, distant metastasis of the left parasternal lymph node metastasis developed. She was treated by further excision and received a total of four regimens of chemotherapy including a combination of doxorubicin and cyclophosphamide. She received chemotherapy for 20 months after the diagnosis of metastasis.http://dx.doi.org/10.1155/2013/164761
spellingShingle Yumi Endo
Hiroshi Sugiura
Hiroko Yamashita
Satoru Takahashi
Nobuyasu Yoshimoto
Mai Iwasa
Tomoko Asano
Tatsuya Toyama
Myoepithelial Carcinoma of the Breast Treated with Surgery and Chemotherapy
Case Reports in Oncological Medicine
title Myoepithelial Carcinoma of the Breast Treated with Surgery and Chemotherapy
title_full Myoepithelial Carcinoma of the Breast Treated with Surgery and Chemotherapy
title_fullStr Myoepithelial Carcinoma of the Breast Treated with Surgery and Chemotherapy
title_full_unstemmed Myoepithelial Carcinoma of the Breast Treated with Surgery and Chemotherapy
title_short Myoepithelial Carcinoma of the Breast Treated with Surgery and Chemotherapy
title_sort myoepithelial carcinoma of the breast treated with surgery and chemotherapy
url http://dx.doi.org/10.1155/2013/164761
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