APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage

APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage

Aim: The aim of this study was to assess the utility of weighted amide proton transfer (APTw) MRI in three different rodent models of hepatocellular carcinoma (HCC).Methods: APTw MRI was evaluated in models of diethylnitrosamine (DEN) induced HCC, N1S1 syngeneic orthotopic xenograft and human HepG2...

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Main Authors: Xiaojing Wang, Keisuke Ishimatsu, Junjie Li, Xiaodong Wen, Weijun Ou, Arnida Anwar, Jaideep Chaudhary, Masaya Takahashi, A Dean Sherry, Ian R Corbin
Format: Article
Language:English
Published: Taylor & Francis 2024-12-01
Series:Hepatic Oncology
Subjects:
docosahexaenoic acid
hepatocellular carcinoma
low-density lipoprotein
molecular imaging
nanoparticle
Online Access:https://www.tandfonline.com/doi/10.1080/20450923.2024.2389031
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