Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 Vaccination

The most common adverse effects of SARS-CoV-2 vaccines are injection site reactions and systemic symptoms, such as fever and malaise, which are typically self-limiting. Multisystem inflammatory syndrome after SARS-CoV-2 vaccination (MIS-V) is rare. In this report, we describe a case of a 22-year-old...

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Bibliographic Details
Main Authors: Yuki Shimada, Masao Takigami, Shunya Kaneshita, Kenji Yanishi, Satoaki Matoba, Yutaka Kawahito
Format: Article
Language:English
Published: American College of Physicians 2022-11-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.0747
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Summary:The most common adverse effects of SARS-CoV-2 vaccines are injection site reactions and systemic symptoms, such as fever and malaise, which are typically self-limiting. Multisystem inflammatory syndrome after SARS-CoV-2 vaccination (MIS-V) is rare. In this report, we describe a case of a 22-year-old man who developed MIS-V with myocardial infarction. Optical coherence tomography (OCT) showed blurring of intravascular structure, intimal thickening, and medial vessel destruction. High-dose glucocorticoid and antithrombotic therapy were effective as shown through improvement in OCT findings.
ISSN:2767-7664