Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis

Cardiac dysfunction is a common complication of sepsis in individuals with preexisting coronary disease and portends a poor prognosis when progressing to ischemic cardiogenic shock. In this setting, maximal medical therapy in isolation is often inadequate to maintain cardiac output for patients who...

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Main Authors: Praveen George, Mukta C. Srivastava, Jonathan Ludmir, Robert M. Reed, Semhar Z. Tewelde, Anuj Gupta, Michael T. McCurdy
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2017/8407530
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author Praveen George
Mukta C. Srivastava
Jonathan Ludmir
Robert M. Reed
Semhar Z. Tewelde
Anuj Gupta
Michael T. McCurdy
author_facet Praveen George
Mukta C. Srivastava
Jonathan Ludmir
Robert M. Reed
Semhar Z. Tewelde
Anuj Gupta
Michael T. McCurdy
author_sort Praveen George
collection DOAJ
description Cardiac dysfunction is a common complication of sepsis in individuals with preexisting coronary disease and portends a poor prognosis when progressing to ischemic cardiogenic shock. In this setting, maximal medical therapy in isolation is often inadequate to maintain cardiac output for patients who are poor candidates for immediate revascularization. Furthermore, the use of vasopressors and inotropes increases myocardial demand and may lead to further injury. Percutaneous ventricular assist devices provide a viable option for management of severe shock with multiorgan failure. The Impella is one of several novel mechanical support systems that can effectively augment cardiac output while reducing myocardial demand and serve as a bridge to recovery from severe hemodynamic compromise. This case report describes the successful utilization of the Impella 2.5 in a patient with baseline profound anemia and coronary artery disease (CAD) presenting in combined distributive and cardiogenic shock associated with a type 2 myocardial infarction complicating sepsis.
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publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Cardiology
spelling doaj-art-395553f91cec4e88b3d160f429383b252025-02-03T05:46:23ZengWileyCase Reports in Cardiology2090-64042090-64122017-01-01201710.1155/2017/84075308407530Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating SepsisPraveen George0Mukta C. Srivastava1Jonathan Ludmir2Robert M. Reed3Semhar Z. Tewelde4Anuj Gupta5Michael T. McCurdy6Department of Internal Medicine, University of Maryland School of Medicine, Baltimore, MD, USADivision of Cardiology, University of Maryland School of Medicine, Baltimore, MD, USADivision of Cardiology, University of Maryland School of Medicine, Baltimore, MD, USADivision of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD, USADepartment of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD, USADivision of Cardiology, University of Maryland School of Medicine, Baltimore, MD, USADivision of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD, USACardiac dysfunction is a common complication of sepsis in individuals with preexisting coronary disease and portends a poor prognosis when progressing to ischemic cardiogenic shock. In this setting, maximal medical therapy in isolation is often inadequate to maintain cardiac output for patients who are poor candidates for immediate revascularization. Furthermore, the use of vasopressors and inotropes increases myocardial demand and may lead to further injury. Percutaneous ventricular assist devices provide a viable option for management of severe shock with multiorgan failure. The Impella is one of several novel mechanical support systems that can effectively augment cardiac output while reducing myocardial demand and serve as a bridge to recovery from severe hemodynamic compromise. This case report describes the successful utilization of the Impella 2.5 in a patient with baseline profound anemia and coronary artery disease (CAD) presenting in combined distributive and cardiogenic shock associated with a type 2 myocardial infarction complicating sepsis.http://dx.doi.org/10.1155/2017/8407530
spellingShingle Praveen George
Mukta C. Srivastava
Jonathan Ludmir
Robert M. Reed
Semhar Z. Tewelde
Anuj Gupta
Michael T. McCurdy
Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis
Case Reports in Cardiology
title Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis
title_full Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis
title_fullStr Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis
title_full_unstemmed Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis
title_short Augmenting Function for Infarction from Infection: Impella 2.5 for Ischemic Cardiogenic Shock Complicating Sepsis
title_sort augmenting function for infarction from infection impella 2 5 for ischemic cardiogenic shock complicating sepsis
url http://dx.doi.org/10.1155/2017/8407530
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