Common variants within MECP2 confer risk of systemic lupus erythematosus.

Common variants within MECP2 confer risk of systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is a predominantly female autoimmune disease that affects multiple organ systems. Herein, we report on an X-chromosome gene association with SLE. Methyl-CpG-binding protein 2 (MECP2) is located on chromosome Xq28 and encodes for a protein that plays a critical role...

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Main Authors: Amr H Sawalha, Ryan Webb, Shizhong Han, Jennifer A Kelly, Kenneth M Kaufman, Robert P Kimberly, Marta E Alarcón-Riquelme, Judith A James, Timothy J Vyse, Gary S Gilkeson, Chan-Bum Choi, R Hal Scofield, Sang-Cheol Bae, Swapan K Nath, John B Harley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001727&type=printable
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