Cutibacterium Acnes induces Alzheimer’s disease-like pathology in brains of wistar rats through structural changes associated with microtubules

Cutibacterium Acnes induces Alzheimer’s disease-like pathology in brains of wistar rats through structural changes associated with microtubules

Abstract Background Cutibacterium acnes ( C. acnes), a Gram-positive anaerobe and a dominant bacterium species in the sebaceous follicles of the face was detected in the brain of Alzheimer’s disease (AD) patients. It has been found that C. acnes activates non-specifically the innate immune system by...

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Main Authors: Morteza Aliashrafi, Mohammad Nasehi, Seyed Davar Siadat, Mohammad-Hossein Mohammadi-Mahdiabadi-Hasani, Hakimeh Zali, Zahra Niknam
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Behavioral and Brain Functions
Subjects:
Cutibacterium acnes
Alzheimer’s disease
Memory
Amyloid-β deposition
Hyperphosphorylated tau
Neurotoxicity
Online Access:https://doi.org/10.1186/s12993-024-00257-8
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https://doi.org/10.1186/s12993-024-00257-8

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