Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel Method
Octyl methoxycinnamate and butyl methoxydibenzoylmethane are organic UV filters with poor photostability and will become photoallergy or phototoxic substance when exposed to ultraviolet radiation. The organic UV filters coated by microcapsules can reduce the photodegradation and avoid direct contact...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2021/8580992 |
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| author | Pey-Shiuan Wu Chia-Hui Lin Yi-Ching Kuo Chih-Chien Lin |
| author_facet | Pey-Shiuan Wu Chia-Hui Lin Yi-Ching Kuo Chih-Chien Lin |
| author_sort | Pey-Shiuan Wu |
| collection | DOAJ |
| description | Octyl methoxycinnamate and butyl methoxydibenzoylmethane are organic UV filters with poor photostability and will become photoallergy or phototoxic substance when exposed to ultraviolet radiation. The organic UV filters coated by microcapsules can reduce the photodegradation and avoid direct contact with the skin. Through microencapsulation, the application of UV filters in cosmetics becomes more effective and safer. This study first used the sol-gel method to create organic/inorganic composite UV filter microcapsules. We used sodium alginate as a shell material of the microcapsule to encapsulate UV filters. CaCO3 and tetraethyl orthosilicate (TEOS) were used as cross-linking agents, and sorbitan monooleate (Span 80) and polyoxyethylenesorbitan monooleate (Tween 80) were used as emulsifiers in the interfacial polymerization method for preparation. The results indicated that the microcapsules with 3 g of CaCO3 cross-linking agents had a similar particle size and better entrapment efficiency. The average sizes were 61.0 ± 4.9 μm and 48.6 ± 4.7 μm, and entrapment efficiencies were 75.3 ± 1.9% and 74.8 ± 1.7% for octyl methoxycinnamate and butyl methoxydibenzoylmethane, respectively. Utilizing sodium alginate as a cross-linking agent is better than TEOS due to the higher calcium content. In vitro transdermal delivery analysis showed that the release rate became steady. |
| format | Article |
| id | doaj-art-3940b3d7a5484ce2bd800bf166c3dade |
| institution | Kabale University |
| issn | 1687-8442 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-3940b3d7a5484ce2bd800bf166c3dade2025-02-03T01:25:20ZengWileyAdvances in Materials Science and Engineering1687-84422021-01-01202110.1155/2021/8580992Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel MethodPey-Shiuan Wu0Chia-Hui Lin1Yi-Ching Kuo2Chih-Chien Lin3Department of Cosmetic ScienceDepartment of Cosmetic ScienceDepartment of Cosmetic ScienceDepartment of Cosmetic ScienceOctyl methoxycinnamate and butyl methoxydibenzoylmethane are organic UV filters with poor photostability and will become photoallergy or phototoxic substance when exposed to ultraviolet radiation. The organic UV filters coated by microcapsules can reduce the photodegradation and avoid direct contact with the skin. Through microencapsulation, the application of UV filters in cosmetics becomes more effective and safer. This study first used the sol-gel method to create organic/inorganic composite UV filter microcapsules. We used sodium alginate as a shell material of the microcapsule to encapsulate UV filters. CaCO3 and tetraethyl orthosilicate (TEOS) were used as cross-linking agents, and sorbitan monooleate (Span 80) and polyoxyethylenesorbitan monooleate (Tween 80) were used as emulsifiers in the interfacial polymerization method for preparation. The results indicated that the microcapsules with 3 g of CaCO3 cross-linking agents had a similar particle size and better entrapment efficiency. The average sizes were 61.0 ± 4.9 μm and 48.6 ± 4.7 μm, and entrapment efficiencies were 75.3 ± 1.9% and 74.8 ± 1.7% for octyl methoxycinnamate and butyl methoxydibenzoylmethane, respectively. Utilizing sodium alginate as a cross-linking agent is better than TEOS due to the higher calcium content. In vitro transdermal delivery analysis showed that the release rate became steady.http://dx.doi.org/10.1155/2021/8580992 |
| spellingShingle | Pey-Shiuan Wu Chia-Hui Lin Yi-Ching Kuo Chih-Chien Lin Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel Method Advances in Materials Science and Engineering |
| title | Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel Method |
| title_full | Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel Method |
| title_fullStr | Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel Method |
| title_full_unstemmed | Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel Method |
| title_short | Preparation and Characterization of Organic/Inorganic Composite UV Filter Microcapsules by Sol-Gel Method |
| title_sort | preparation and characterization of organic inorganic composite uv filter microcapsules by sol gel method |
| url | http://dx.doi.org/10.1155/2021/8580992 |
| work_keys_str_mv | AT peyshiuanwu preparationandcharacterizationoforganicinorganiccompositeuvfiltermicrocapsulesbysolgelmethod AT chiahuilin preparationandcharacterizationoforganicinorganiccompositeuvfiltermicrocapsulesbysolgelmethod AT yichingkuo preparationandcharacterizationoforganicinorganiccompositeuvfiltermicrocapsulesbysolgelmethod AT chihchienlin preparationandcharacterizationoforganicinorganiccompositeuvfiltermicrocapsulesbysolgelmethod |