Degradation of amyloid β-peptides catalyzed by nattokinase in vivo and in vitro
Amyloid-β 1-42 (Aβ42) plays a pivotal role in Alzheimer disease (AD) pathogenesis. Peripheral clearance of Aβ42 largely affects its level in the brain and affects AD progression. Although nattokinase (NK) degrades Aβ40, the details of NK’s capture of various Aβ species and reduction of plasma Aβ42/A...
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Main Authors: | Aixin Ni, He Li, Ruya Wang, Rentong Sun, Yingjiu Zhang |
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Format: | Article |
Language: | English |
Published: |
Tsinghua University Press
2023-09-01
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Series: | Food Science and Human Wellness |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453023000423 |
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