Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South India

Background: Pediatric risk of mortality (PRISM III) score and pediatric index of mortality (PIM III) scores are most recent versions of PRISM and PIM score used for mortality prediction in the Pediatric intensive care units (PICUs). This study aims to compare the performance of these two scores in c...

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Main Authors: Nidhi Srinivas, Kavya Venugopal, Gurudutta Avathi Venkatesha, Nagalatha Chidanand
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-09-01
Series:Journal of Pediatric Critical Care
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Online Access:https://journals.lww.com/10.4103/jpcc.jpcc_32_24
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author Nidhi Srinivas
Kavya Venugopal
Gurudutta Avathi Venkatesha
Nagalatha Chidanand
author_facet Nidhi Srinivas
Kavya Venugopal
Gurudutta Avathi Venkatesha
Nagalatha Chidanand
author_sort Nidhi Srinivas
collection DOAJ
description Background: Pediatric risk of mortality (PRISM III) score and pediatric index of mortality (PIM III) scores are most recent versions of PRISM and PIM score used for mortality prediction in the Pediatric intensive care units (PICUs). This study aims to compare the performance of these two scores in children admitted to a tertiary PICU of South India. Subjects and Methods: This single-center, prospective observational study was conducted in PICU at a Tertiary Care Hospital in South India over a period of 20 months. A total of 214 cases admitted between the age groups of 1 month and 18 years were included in this study. PIM III and PRISM III scores were calculated. Quantitative correlation between the results of the score was analyzed by spearman test. Discrimination was assessed using the area under receiver operating characteristics curve and calibration using Hosmer–Lemeshow goodness-of-fit test. Results: Out of 214 children, observed mortality was 11 (5.1%). Estimated mortality using PRISM III and PIM III was 4 (1.86%) and 2 (0.93%), respectively. Although both scoring systems had good discrimination performance, PIM III score (0.934 [confidence interval (CI) 95%, 0.886–0.982]) had higher discrimination than PRISM III score(0.888 [CI 95%, 0.797–0.980]). PRISM III score (χ2 = 4.469 and P = 0.484) had better calibration as compared to PIM III score (χ2 = 16.093 and P = 0.041). Conclusions: Both PRISM III and PIM III score showed good discriminatory performance, however PRISM III had better calibration than PIM III score.
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spelling doaj-art-392d32fb44f54388861bd8b9ecb33fb52025-01-23T06:03:17ZengWolters Kluwer Medknow PublicationsJournal of Pediatric Critical Care2349-65922455-70992024-09-0111520821210.4103/jpcc.jpcc_32_24Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South IndiaNidhi SrinivasKavya VenugopalGurudutta Avathi VenkateshaNagalatha ChidanandBackground: Pediatric risk of mortality (PRISM III) score and pediatric index of mortality (PIM III) scores are most recent versions of PRISM and PIM score used for mortality prediction in the Pediatric intensive care units (PICUs). This study aims to compare the performance of these two scores in children admitted to a tertiary PICU of South India. Subjects and Methods: This single-center, prospective observational study was conducted in PICU at a Tertiary Care Hospital in South India over a period of 20 months. A total of 214 cases admitted between the age groups of 1 month and 18 years were included in this study. PIM III and PRISM III scores were calculated. Quantitative correlation between the results of the score was analyzed by spearman test. Discrimination was assessed using the area under receiver operating characteristics curve and calibration using Hosmer–Lemeshow goodness-of-fit test. Results: Out of 214 children, observed mortality was 11 (5.1%). Estimated mortality using PRISM III and PIM III was 4 (1.86%) and 2 (0.93%), respectively. Although both scoring systems had good discrimination performance, PIM III score (0.934 [confidence interval (CI) 95%, 0.886–0.982]) had higher discrimination than PRISM III score(0.888 [CI 95%, 0.797–0.980]). PRISM III score (χ2 = 4.469 and P = 0.484) had better calibration as compared to PIM III score (χ2 = 16.093 and P = 0.041). Conclusions: Both PRISM III and PIM III score showed good discriminatory performance, however PRISM III had better calibration than PIM III score.https://journals.lww.com/10.4103/jpcc.jpcc_32_24mortalitypediatric index of mortality iiipediatric risk of mortality iiisurvival
spellingShingle Nidhi Srinivas
Kavya Venugopal
Gurudutta Avathi Venkatesha
Nagalatha Chidanand
Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South India
Journal of Pediatric Critical Care
mortality
pediatric index of mortality iii
pediatric risk of mortality iii
survival
title Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South India
title_full Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South India
title_fullStr Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South India
title_full_unstemmed Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South India
title_short Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South India
title_sort comparison of pediatric risk of mortality prism iii score with pediatric index of mortality pim iii score in pediatric intensive care unit a single center prospective observational study from south india
topic mortality
pediatric index of mortality iii
pediatric risk of mortality iii
survival
url https://journals.lww.com/10.4103/jpcc.jpcc_32_24
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