Sleep-related drugs utilization and suicide behaviors: a population-based study in China
Abstract Background Previous studies have yielded conflicting findings regarding the relationship between the use of sleep-related drugs (SRDU) and suicidal behaviors. This population-based study aimed to analyze the associations between SRDU and suicidal behaviors. Additionally, we examined the ass...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s12889-025-21443-x |
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| author | Yunshu Zhang Bo Liu Keqing Li Hailing Jia Hemin Shi Yongqiao Liu Jianfeng Li Long Sun |
| author_facet | Yunshu Zhang Bo Liu Keqing Li Hailing Jia Hemin Shi Yongqiao Liu Jianfeng Li Long Sun |
| author_sort | Yunshu Zhang |
| collection | DOAJ |
| description | Abstract Background Previous studies have yielded conflicting findings regarding the relationship between the use of sleep-related drugs (SRDU) and suicidal behaviors. This population-based study aimed to analyze the associations between SRDU and suicidal behaviors. Additionally, we examined the associations between SRDU and specific conditional suicidal behaviors, providing insights into the impact of SRDU on the progression of suicidal behaviors. Methods The study was conducted among community residents aged 18 and older using a cross-sectional design, analyzing 21,376 participants. Data on SRDU, suicidal ideation, plans, and attempts were collected. Participants were categorized into general individuals without suicidal behaviors (GNS), suicidal ideators without a plan or attempt (SINPA), suicidal ideators with a plan but no attempt (SIP), and individuals who attempted suicide (SA). Insomnia, sleep apnea, rapid eye movement sleep behavior disorder (RBD), and narcolepsy were assessed using the Athens Insomnia Scale, Berlin Questionnaire, Rapid Eye Movement Sleep Behavior Disorder Questionnaire, and Ullanlinna Narcolepsy Scale, respectively. Results After adjusting for sociodemographic variables, insomnia, sleep apnea, RBD, and narcolepsy, SRDU showed a positive association with suicidal ideation (OR = 3.02), plans (OR = 4.78), and attempts (OR = 6.40; all p < 0.001). Compared to GNS, and after controlling for the same variables, SRDU was associated with SINPA (OR = 2.46), SIP (OR = 5.11), and SA (OR = 6.93; all p < 0.001) respectively. However, no significant differences in SRDU were found between SINPA, SIP, and SA (all p > 0.05). Conclusions This population-based study confirms that SRDU is positively associated with suicidal ideation, plans, and attempts, even after accounting for the risk factors of insomnia, sleep apnea, RBD, and narcolepsy. Nonetheless, SRDU does not appear to influence the progression from suicidal ideation to attempt. |
| format | Article |
| id | doaj-art-392c832b45ab49a9abf532c3687acdf5 |
| institution | Kabale University |
| issn | 1471-2458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj-art-392c832b45ab49a9abf532c3687acdf52025-01-26T12:56:28ZengBMCBMC Public Health1471-24582025-01-012511910.1186/s12889-025-21443-xSleep-related drugs utilization and suicide behaviors: a population-based study in ChinaYunshu Zhang0Bo Liu1Keqing Li2Hailing Jia3Hemin Shi4Yongqiao Liu5Jianfeng Li6Long Sun7Hebei Provincial Mental Health CenterThe Sixth Clinical Medical College of Hebei UniversityThe Sixth Clinical Medical College of Hebei UniversityThe Sixth Clinical Medical College of Hebei UniversityThe Sixth Clinical Medical College of Hebei UniversityThe Sixth Clinical Medical College of Hebei UniversityThe Sixth Clinical Medical College of Hebei UniversityCentre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong UniversityAbstract Background Previous studies have yielded conflicting findings regarding the relationship between the use of sleep-related drugs (SRDU) and suicidal behaviors. This population-based study aimed to analyze the associations between SRDU and suicidal behaviors. Additionally, we examined the associations between SRDU and specific conditional suicidal behaviors, providing insights into the impact of SRDU on the progression of suicidal behaviors. Methods The study was conducted among community residents aged 18 and older using a cross-sectional design, analyzing 21,376 participants. Data on SRDU, suicidal ideation, plans, and attempts were collected. Participants were categorized into general individuals without suicidal behaviors (GNS), suicidal ideators without a plan or attempt (SINPA), suicidal ideators with a plan but no attempt (SIP), and individuals who attempted suicide (SA). Insomnia, sleep apnea, rapid eye movement sleep behavior disorder (RBD), and narcolepsy were assessed using the Athens Insomnia Scale, Berlin Questionnaire, Rapid Eye Movement Sleep Behavior Disorder Questionnaire, and Ullanlinna Narcolepsy Scale, respectively. Results After adjusting for sociodemographic variables, insomnia, sleep apnea, RBD, and narcolepsy, SRDU showed a positive association with suicidal ideation (OR = 3.02), plans (OR = 4.78), and attempts (OR = 6.40; all p < 0.001). Compared to GNS, and after controlling for the same variables, SRDU was associated with SINPA (OR = 2.46), SIP (OR = 5.11), and SA (OR = 6.93; all p < 0.001) respectively. However, no significant differences in SRDU were found between SINPA, SIP, and SA (all p > 0.05). Conclusions This population-based study confirms that SRDU is positively associated with suicidal ideation, plans, and attempts, even after accounting for the risk factors of insomnia, sleep apnea, RBD, and narcolepsy. Nonetheless, SRDU does not appear to influence the progression from suicidal ideation to attempt.https://doi.org/10.1186/s12889-025-21443-xSleep-related drug utilizationSuicidal ideationSuicide planSuicide attemptPopulation-based study |
| spellingShingle | Yunshu Zhang Bo Liu Keqing Li Hailing Jia Hemin Shi Yongqiao Liu Jianfeng Li Long Sun Sleep-related drugs utilization and suicide behaviors: a population-based study in China BMC Public Health Sleep-related drug utilization Suicidal ideation Suicide plan Suicide attempt Population-based study |
| title | Sleep-related drugs utilization and suicide behaviors: a population-based study in China |
| title_full | Sleep-related drugs utilization and suicide behaviors: a population-based study in China |
| title_fullStr | Sleep-related drugs utilization and suicide behaviors: a population-based study in China |
| title_full_unstemmed | Sleep-related drugs utilization and suicide behaviors: a population-based study in China |
| title_short | Sleep-related drugs utilization and suicide behaviors: a population-based study in China |
| title_sort | sleep related drugs utilization and suicide behaviors a population based study in china |
| topic | Sleep-related drug utilization Suicidal ideation Suicide plan Suicide attempt Population-based study |
| url | https://doi.org/10.1186/s12889-025-21443-x |
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