Gut Microbiota and Obesity
Obesity is a global health concern associated with a wide range of diseases, including diabetes, metabolic syndrome, fatty liver, and cardiovascular conditions. Recent studies highlight the significant role of gut microbiota in obesity. Research indicates notable changes in the composition and diver...
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| Format: | Article |
| Language: | English |
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Korean College of Helicobacter and Upper Gastrointestinal Research
2023-12-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://helicojournal.org/upload/pdf/kjhugr-2023-0057.pdf |
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| _version_ | 1849415294507810816 |
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| author | Seung Young Kim |
| author_facet | Seung Young Kim |
| author_sort | Seung Young Kim |
| collection | DOAJ |
| description | Obesity is a global health concern associated with a wide range of diseases, including diabetes, metabolic syndrome, fatty liver, and cardiovascular conditions. Recent studies highlight the significant role of gut microbiota in obesity. Research indicates notable changes in the composition and diversity of gut microbiota in individuals diagnosed with obesity. The gut microbiota participate in energy metabolism, lipid synthesis, and regulation of inflammation and therefore play a key role in the pathogenesis of obesity. Therapeutic approaches based on the use of probiotics, prebiotics, Akkermansia muciniphila, and fecal microbiota transplantation have shown promise in animal studies as useful strategies against obesity and metabolic syndrome. However, further research is warranted to conclusively establish the specific strains, dosages, and mechanisms underlying the effectiveness of these novel strategies against obesity in humans. |
| format | Article |
| id | doaj-art-392633ac0605478cb3c2f814c1683f65 |
| institution | Kabale University |
| issn | 1738-3331 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-392633ac0605478cb3c2f814c1683f652025-08-20T03:33:35ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312023-12-0123424024610.7704/kjhugr.2023.0057800Gut Microbiota and ObesitySeung Young KimObesity is a global health concern associated with a wide range of diseases, including diabetes, metabolic syndrome, fatty liver, and cardiovascular conditions. Recent studies highlight the significant role of gut microbiota in obesity. Research indicates notable changes in the composition and diversity of gut microbiota in individuals diagnosed with obesity. The gut microbiota participate in energy metabolism, lipid synthesis, and regulation of inflammation and therefore play a key role in the pathogenesis of obesity. Therapeutic approaches based on the use of probiotics, prebiotics, Akkermansia muciniphila, and fecal microbiota transplantation have shown promise in animal studies as useful strategies against obesity and metabolic syndrome. However, further research is warranted to conclusively establish the specific strains, dosages, and mechanisms underlying the effectiveness of these novel strategies against obesity in humans.http://helicojournal.org/upload/pdf/kjhugr-2023-0057.pdfobesitymicrobiotaprobioticsprebiotics |
| spellingShingle | Seung Young Kim Gut Microbiota and Obesity The Korean Journal of Helicobacter and Upper Gastrointestinal Research obesity microbiota probiotics prebiotics |
| title | Gut Microbiota and Obesity |
| title_full | Gut Microbiota and Obesity |
| title_fullStr | Gut Microbiota and Obesity |
| title_full_unstemmed | Gut Microbiota and Obesity |
| title_short | Gut Microbiota and Obesity |
| title_sort | gut microbiota and obesity |
| topic | obesity microbiota probiotics prebiotics |
| url | http://helicojournal.org/upload/pdf/kjhugr-2023-0057.pdf |
| work_keys_str_mv | AT seungyoungkim gutmicrobiotaandobesity |