Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Disease...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2021/9933319 |
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| author | Brenda M. Galindo-Yllu Ricardo Rojas-Humpire Carlos J. Toro-Huamanchumo Rosmery Gutierrez-Ajalcriña Anderson N. Soriano |
| author_facet | Brenda M. Galindo-Yllu Ricardo Rojas-Humpire Carlos J. Toro-Huamanchumo Rosmery Gutierrez-Ajalcriña Anderson N. Soriano |
| author_sort | Brenda M. Galindo-Yllu |
| collection | DOAJ |
| description | We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Diseases of Huaycán Hospital. MetS was defined according to Latin American Diabetes Association (ALAD) criteria and IR with surrogate IR markers, triglyceride-to-HDL-C ratio (TG/HDL-C), and triglyceride-to-glucose index (TyG). The association between SUA and MetS and IR was determined using Poisson regression models in a sample of 292 participants with an average age of 46.2 ± 10.6 years. The total prevalence of MetS was 38%, and the individuals with MetS presented mainly alterations in anthropometric parameters (obesity and body fat). Finally, the adjusted regression models showed that women with SUA in the highest tertile increased the prevalence of MetS (PR: 1.71, 95% CI: 1.07–2.74) compared to the lowest tertile of SUA in women, while SUA increased hypertriglyceridemia and IR (TG/HDL-C and TyG) in both sexes. We concluded that SUA is strongly associated with MetS in women, and SUA increases hypertriglyceridemia and IR in both sexes. On the contrary, more research is required regarding the female population. |
| format | Article |
| id | doaj-art-38f48b94912040bc959b722887ea16a6 |
| institution | Kabale University |
| issn | 2090-0732 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-38f48b94912040bc959b722887ea16a62025-02-03T06:43:23ZengWileyJournal of Nutrition and Metabolism2090-07322021-01-01202110.1155/2021/9933319Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from PeruBrenda M. Galindo-Yllu0Ricardo Rojas-Humpire1Carlos J. Toro-Huamanchumo2Rosmery Gutierrez-Ajalcriña3Anderson N. Soriano4Clinical and Epidemiological Research UnitClinical and Epidemiological Research UnitUniversidad San Ignacio de LoyolaUnidad de Epidemiología y Salud AmbientalClinical and Epidemiological Research UnitWe explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Diseases of Huaycán Hospital. MetS was defined according to Latin American Diabetes Association (ALAD) criteria and IR with surrogate IR markers, triglyceride-to-HDL-C ratio (TG/HDL-C), and triglyceride-to-glucose index (TyG). The association between SUA and MetS and IR was determined using Poisson regression models in a sample of 292 participants with an average age of 46.2 ± 10.6 years. The total prevalence of MetS was 38%, and the individuals with MetS presented mainly alterations in anthropometric parameters (obesity and body fat). Finally, the adjusted regression models showed that women with SUA in the highest tertile increased the prevalence of MetS (PR: 1.71, 95% CI: 1.07–2.74) compared to the lowest tertile of SUA in women, while SUA increased hypertriglyceridemia and IR (TG/HDL-C and TyG) in both sexes. We concluded that SUA is strongly associated with MetS in women, and SUA increases hypertriglyceridemia and IR in both sexes. On the contrary, more research is required regarding the female population.http://dx.doi.org/10.1155/2021/9933319 |
| spellingShingle | Brenda M. Galindo-Yllu Ricardo Rojas-Humpire Carlos J. Toro-Huamanchumo Rosmery Gutierrez-Ajalcriña Anderson N. Soriano Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru Journal of Nutrition and Metabolism |
| title | Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru |
| title_full | Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru |
| title_fullStr | Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru |
| title_full_unstemmed | Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru |
| title_short | Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru |
| title_sort | serum uric acid is associated with metabolic syndrome and insulin resistance among health personnel from peru |
| url | http://dx.doi.org/10.1155/2021/9933319 |
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