Antibody responses against influenza A decline with successive years of annual influenza vaccination

Antibody responses against influenza A decline with successive years of annual influenza vaccination

Abstract Influenza vaccine effectiveness and immunogenicity can be compromised with repeated vaccination. We assessed immunological markers in a cohort of healthcare workers (HCW) from six public hospitals around Australia during 2020–2021. Sera were collected pre-vaccination and ~14 and ~180 days p...

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Main Authors: Sheena G. Sullivan, Arseniy Khvorov, Louise Carolan, Leslie Dowson, A. Jessica Hadiprodjo, Stephany Sánchez-Ovando, Yi Liu, Vivian K. Y. Leung, David Hodgson, Christopher C. Blyth, Marion Macnish, Allen C. Cheng, Michelle Haugenauer, Julia Clark, Sonia Dougherty, Kristine Macartney, Archana Koirala, Ameneh Khatami, Ajay Jadhav, Helen Marshall, Kathryn E. Riley, Peter A. B. Wark, Catherine Delahunty, Kanta Subbarao, Adam J. Kucharski, Annette Fox
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-01057-x
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